Protein Alignment smid and PEX6

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_171799.2
• Gene: PEX6 / 839315
• AraportID: AT1G03000
• Length: 941
• Species: Arabidopsis thaliana
• Alignment Length: 758
• Identity: 215/758 - (28%)
• Similarity: 337/758 - (44%)
• Gaps: 203/758 - (26%)

  Fly   238 KRDLEVQHPTESFRDIGGMDST-----------------LKELCEMLIHIKSPEFYFQLGLLPSR 285
            :|.|.|.| :::...:||..|:                 .:|...:|..:.||.      |.||.
plant   314 ERFLRVNH-SQTALVLGGTVSSGLPPDLLVYRSKVPMPLQEETVNILASVLSPP------LCPSA 371

  Fly   286 -------GLLLHGPPGCGKTFLARAISGQLKMPLMEIPATELIGGISGESEERIREVFDQAIGYS 343
                   .:||||.|||||..:.:.::.:|.:.::|.....|:.....::...:.:.|:.|..||
plant   372 LASKLRVAVLLHGIPGCGKRTVVKYVARRLGLHVVEFSCHSLLASSERKTSTALAQTFNMARRYS 436

  Fly   344 PCVLFIDEIDA---IG------GNRQWASKDMERRI------VSQLISSLD-----NLKANEFGQ 388
            |.:|.:...|.   :|      |:|...|.::...|      ||...||::     |...||.|:
plant   437 PTILLLRHFDVFKNLGSQDGSLGDRVGVSFEIASVIRELTEPVSNGDSSMEEKSNSNFSENEVGK 501

  Fly   389 ----SVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKLNYDK-- 447
                .|::||:....:.:.|.:||.  |.|||.:...:.::|.|:|....:|:|....::.|:
plant   502 FRGHQVLLIASAESTEGISPTIRRC--FSHEIRMGSLNDEQRSEMLSQSLQGVSQFLNISSDEFM 564

  Fly   448 --IAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTV-TLDDDEPSEDAGETP 509
              :...|.|::..||.|||:.|.:            .|:.:.|.....: :|.||....|..:..
plant   565 KGLVGQTSGFLPRDLQALVADAGA------------NLYISQESETKKINSLSDDLHGVDIHQAS 617

  Fly   510 VPDSKGEE-TAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSIKSPQKTPKKSAEK 573
            ..|:..|: |||          :..|.|.|:|:                          |::|.
plant   618 QIDNSTEKLTAK----------EDFTKALDRSK--------------------------KRNAS- 645

  Fly   574 PTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDFV 638
                       |...||
plant   646 -----------ALGAPK------------------------------------------------ 651

  Fly   639 DAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCG 703
                             ||:..|||:|.||.::..:...|..|:.:.::... ||...|||||.|
plant   652 -----------------VPNVKWDDVGGLEDVKTSILDTVQLPLLHKDLFSS-GLRKRSGVLLYG 698

  Fly   704 PPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLC 768
            |||.||||||||:|.|..:||:|||||||:|||:||||:.||..|::||::.||||||||.|||.
plant   699 PPGTGKTLLAKAVATECSLNFLSVKGPELINMYIGESEKNVRDIFEKARSARPCVIFFDELDSLA 763

  Fly   769 PKRSDGGDGNNSGTRIVNQLLTEMDGV-EERKGVYILAATNRPDIIDPAILRPGRLDTILYVGF- 831
            |.|...||......|:|:|:|.|:||: :..:.::|:.|:||||:||||:|||||.|.:||||.
plant   764 PARGASGDSGGVMDRVVSQMLAEIDGLSDSSQDLFIIGASNRPDLIDPALLRPGRFDKLLYVGVN 828

  Fly   832 PEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEG-YTGADLAGLVKQASMFSLRQSLNNGDT 895
            .:.|.|..:|||.|:..|   |::||.|..:|.:... :||||:..|...|...:.::.::..|:
plant   829 ADASYRERVLKALTRKFK---LSEDVSLYSVAKKCPSTFTGADMYALCADAWFQAAKRKVSKSDS 890

  Fly   896 --------NLDDLCVRSQHFQEALQQLRPSVNEQDRKIYDKLR 930
                    :.|.:.|....|.:|:.||.||::..:.|.|:.||
plant   891 GDMPTEEDDPDSVVVEYVDFIKAMDQLSPSLSITELKKYEMLR 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	213/754 (28%)
PEX6	NP_171799.2	CDC48	<380..937	CDD:273521	201/685 (29%)
		RecA-like_PEX6_r2	666..825	CDD:410935	83/159 (52%)