DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and RPT4A

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_199115.1	Gene:	RPT4A / 834316	AraportID:	AT5G43010	Length:	399	Species:	Arabidopsis thaliana

Alignment Length:	426	Identity:	127/426 - (29%)
Similarity:	209/426 - (49%)	Gaps:	66/426 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   508 TPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATN-GNSSIKSPQKTPKKSA 571
            |.|.:|....||..:|..:|:...||..::.::..:  |:...||..| ....:||.|...:...
plant     2 TDVDESVRRRTAAVSEYRKKLLQHKELESRVRTARE--NLRGAKKEFNKTEDDLKSLQSVGQIIG 64

  Fly   572 E--KPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYY-----EPTLAELTN----FLDNPPEEF 625
            |  :|      :||          |:.:..:||...|.     :....:||:    .||
plant    65 EVLRP------LDN----------ERLIVKASSGPRYVVGCRSKVDKEKLTSGTRVVLD------ 107

  Fly   626 ADPNFCLTLIDFVDAI-KVMQPSAKREGFITVPDTTWDDIGAL-EKIREELKLAVLAPVKYPEML 688
                  :|.:..:.|: :.:.|...........:.::..:|.| ::|| ||:.::..|:..||:.
plant   108 ------MTTLTIMRALPREVDPVVYNMLHEDPGNISYSAVGGLGDQIR-ELRESIELPLMNPELF 165

  Fly   689 ERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARN 753
            .|:|:..|.||||.||||.||||||:|||:....||:.|....:::.|:|||.|.:|..|..||.
plant   166 LRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKVVSSAIIDKYIGESARLIREMFNYARE 230

  Fly   754 SAPCVIFFDEFDSLCPKR-SDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAI 817
            ..||:||.||.|::..:| |:|...:....|.:.:||.::||.:....|.::.||||||::|||:
plant   231 HQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDNLGKVKMIMATNRPDVLDPAL 295

  Fly   818 LRPGRLDTILYVGFPEQSERTEILK----ATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLV 878
            |||||||..:.:..|.:..|.:|||    ...|:|       ::|.:.|....||:.||||..:.
plant   296 LRPGRLDRKIEIPLPNEQSRMDILKIHAAGIAKHG-------EIDYEAIVKLAEGFNGADLRNIC 353

  Fly   879 KQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQL 914
            .:|.||::|...:         .|..:.|.:|:::|
plant   354 TEAGMFAIRAERD---------YVIHEDFMKAVRKL 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	127/426 (30%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	20/36 (56%)
		AAA	699..830	CDD:278434	60/131 (46%)
RPT4A	NP_199115.1	RPT1	17..390	CDD:224143	122/411 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910