DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment smid and yme1l1a

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_005162918.1	Gene:	yme1l1a / 793098	ZFINID:	ZDB-GENE-091113-41	Length:	729	Species:	Danio rerio

Alignment Length:	375	Identity:	115/375 - (30%)
Similarity:	172/375 - (45%)	Gaps:	66/375 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   557 NSSIKSPQKTP--KKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLD 619
            |...|:..|:.  :.|:|.|.:|    ||..|...|..:.:|...:.|.::..:.         :
Zfish   155 NRGFKTMSKSRHLRSSSEGPVEA----DNYTPVFMKGLMMKEKTDTGSLEQLLKQ---------N 206

  Fly   620 NPPEEFAD---PNFCLTLIDFVDAIKVMQPSAKREGFI----------------------TVPDT 659
            |.||...|   ..|....:......|..|.|.||...|                      :..||
Zfish   207 NLPESHQDAFKTGFTEGFMKAQALTKRTQDSVKRTRLIIFVLLLAGIYGVSRSPFFSGKGSFSDT 271

  Fly   660 ---------------------TWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCG 703
                                 |::.:..:|:.:.||: .|:..::.|:....||...|.|:||.|
Zfish   272 VRFRTTSGLDSSVDPVQMKNITFEHVKGVEEAKNELQ-DVVEFLRNPQKFTVLGGKLPKGILLVG 335

  Fly   704 PPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLC 768
            |||.||||||:|:|.||.:.|....|.|...|:||.....:|..|:.|:.|||||||.||.||:.
Zfish   336 PPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFKEAKASAPCVIFIDELDSVG 400

  Fly   769 PKRSDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPE 833
            .||.: ...:....:.:||||.||||.:..:||.::.|||..:.:|.|::||||.|..:.|..|:
Zfish   401 GKRIE-SPMHPYSRQTINQLLAEMDGFKPNEGVIVIGATNFAEALDNALVRPGRFDMQVTVPIPD 464

  Fly   834 QSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASM 883
            ...|||||:...|..|   :...:|.:.||..|.|::||:|..||.||::
Zfish   465 VKGRTEILEWYLKKIK---VDSAIDAEIIARGTVGFSGAELENLVNQAAL 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	115/375 (31%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	17/36 (47%)
		AAA	699..830	CDD:278434	58/130 (45%)
yme1l1a	XP_005162918.1	P-loop_NTPase	287..>351	CDD:304359	24/64 (38%)
		FtsH_fam	289..722	CDD:273520	89/228 (39%)
		AAA	331..461	CDD:278434	58/130 (45%)
		Peptidase_M41	542..720	CDD:279742
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910