Protein Alignment smid and pex6

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: XP_001332652.6
• Gene: pex6 / 792998
• ZFINID: ZDB-GENE-081104-252
• Length: 1071
• Species: Danio rerio
• Alignment Length: 697
• Identity: 207/697 - (29%)
• Similarity: 321/697 - (46%)
• Gaps: 175/697 - (25%)

  Fly   255 GMDSTLKELCEMLIHIKSPEFYFQLGLLPSRG--LLLHGPPGCGKTFLARAISGQLKMPLMEIPA 317
            |:.||:    |.||.|..|... :..|:..||  :||.||.|.||....||:|.:|.:.|:::..
Zfish   533 GLSSTV----EKLITIIQPHLN-ESTLILKRGCSILLMGPNGSGKFTAVRAVSRRLHLHLIKVDC 592

  Fly   318 TELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKDMERRIVS---QLISSLD 379
            ..|....:..||.:|:.||::|..:.||:|.:..:..:|.:|..|..|.  |:.:   |||:::.
Zfish   593 VTLCADTAAASEAKIKSVFERAELHHPCLLLLRNLQLLGQSRDGAETDC--RVAATLCQLIAAVH 655

  Fly   380 NLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKLN 444
            .        ||||:.:.:....|...:  :..|.|::||...|..:||.:|....|.|.:...:|
Zfish   656 T--------SVVVVGSVSSQHELPSDV--MAAFVHQVAIESLSEDQRRTVLSSLSEDLLLGKDVN 710

  Fly   445 YDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVTLDDDEPSEDAGETP 509
            ..:||:.|.|:|..||.||::.|...|.:|                              ..||.
Zfish   711 LGRIAKQTAGFVLGDLCALLTNAGKAAHRR------------------------------LVETY 745

  Fly   510 VPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSIKSPQKTPKKSAEKP 574
            .|::..|:..:|
Zfish   746 FPEAVSEQEEED----------------------------------------------------- 757

  Fly   575 TDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDFVD 639
                :.|..|:                                              :|..||..
Zfish   758 ----LCVSGVS----------------------------------------------VTSEDFSA 772

  Fly   640 AIKVMQPS-AKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCG 703
            |:.|:|.: ::..|...:|..:|.|:|.|:::::|:...:..|:::||:|. |||.. ||:||.|
Zfish   773 ALDVLQEAHSQAIGAPKIPAVSWQDVGGLQQVKKEILDTIQLPLEHPELLS-LGLRR-SGLLLYG 835

  Fly   704 PPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLC 768
            |||.||||||||:|.|..:.|:|||||||:|||||:||..:|..|.:||::|||:|||||.|||.
Zfish   836 PPGTGKTLLAKAVATECTMTFLSVKGPELINMYVGQSEENIRQVFSKARSAAPCIIFFDELDSLA 900

  Fly   769 PKRSDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPE 833
            |.|...||......|:|:|||.|:||:.....|:::.||||||::|.::|||||.|.::|||..|
Zfish   901 PNRGHSGDSGGVMDRVVSQLLAELDGLHSSGDVFVIGATNRPDLLDQSLLRPGRFDKLVYVGINE 965

  Fly   834 QSE-RTEILKATTKNGKRPVLADDVDL-----DEIAAQTEGYTGADLAGLVKQASMFSLRQSLN- 891
            ..| :.::|||..:..|       ||.     |.:.:.....|||||..|...|.|.::::.::
Zfish   966 DRESQLQVLKAILRKFK-------VDASVCLSDIVESCPPRLTGADLYSLCSDAMMCAVKRKISR 1023

  Fly   892 ---NGDTNLDDLCVRSQHFQEALQQLRPSVNEQDRKIYDKLRLKYAA 935
               ..|:.|..|.:.|:.|.|||..|:|||:||....|..|:.|.::
Zfish  1024 ITEGVDSELSSLTLCSEDFSEALSGLQPSVSEQQISRYQLLQQKLSS 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	206/693 (30%)
pex6	XP_001332652.6	None