DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AT5G52882

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_001078747.1	Gene:	AT5G52882 / 5008305	AraportID:	AT5G52882	Length:	829	Species:	Arabidopsis thaliana

Alignment Length:	772	Identity:	184/772 - (23%)
Similarity:	308/772 - (39%)	Gaps:	175/772 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 IGGMDSTL----------KELCEML-----IHIKSPEF-YFQLGLLP-SRGLLLHGPPGCGKTFL 300
            :.|.:||:          |...|:|     :|:|..:. .....|.| |:.:||.||....:..|
plant    55 VDGRESTVTFEEFPYFLSKRTRELLTSVAYVHLKEYDISKHTRNLAPASKAILLSGPAEFYQQML 119

  Fly   301 ARAISGQLKMPLMEIPATELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGN------- 358
            |:|:|...:..|:.:..|:....|..:.....||.|.:.   |...|.:|::.::.|:
plant   120 AKALSHYFESKLLLLDITDFSIKIQSKYGCTKREPFHKR---SISELTLDKVSSLMGSFSMLSQR 181

  Fly   359 ---------RQWASKDMERRIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGR--F 412
                     |..:..|::.| .::..:.|...|.|....|.:...::.....:....:|...  |
plant   182 EVEPRGTLRRHTSGNDLKSR-STESSNRLPRHKRNASAASDISSISSRSSSSVSASRKRTTNLCF 245

  Fly   413 DHEIAIHIPSRKERREILRIQCEGLSVDPKLNY----DKIAELTPGY---------VGADLMALV 464
            |.::.:        :.:.::........|.:.|    :|:.|....|         :...::.|.
plant   246 DEKLFL--------QSLYKVLSSVSETTPLIIYLRDVEKLLESERFYKLFQRLLNKLSGPVLILG 302

  Fly   465 SRAAS-------------------------------VAVKRRSMKKFRELHAASEKNMTTVTLD- 497
            ||...                               |:.|.|.....:.:.....||.....|.
plant   303 SRVLEPEDDCQEVDESISALFPYNIEIRPPEDESQLVSWKSRLEDDMKMIQFQDNKNHIAEVLAA 367

  Fly   498 -----DDEPSEDAGETPVPDSKGEETAKDA---------EAEQKVDGDKETSAKDKSEGDSPNIE 548
                 ||..|....:|....:..||....|         |.|.: :|....|:|..|.|.|...|
plant   368 NDIQCDDLSSICHADTMCLSNHIEEIVVSAITYHLIHTKEPEYR-NGKLVISSKSLSHGLSIFQE 431

  Fly   549 TPKKATNGNSSIKSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVD-SSSSNDEYYEPTLA 612
                  .||.|.:...|....:..|.....:...:.:...|:...|.|:. .|:.||....|...
plant   432 ------GGNRSFEDSLKLDTNTDSKRKGGEVCSKSESKSGPENKNESEISLPSNKNDNPLPPKAP 490

  Fly   613 ELTNFLDNPPEEFADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLA 677
            |:.     |..||.               |.::|.......|.|   |:.|||:|::.::.|:..
plant   491 EVV-----PDNEFE---------------KRIRPEVIPANEIGV---TFADIGSLDETKDSLQEL 532

  Fly   678 VLAPVKYPEMLERLGLTAP-SGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESE 741
            |:.|::.|::.:. ||..| .|:||.||||.|||:||||||||||.:||:|....:.:.:.||.|
plant   533 VMLPLRRPDLFQG-GLLKPCRGILLFGPPGTGKTMLAKAIANEAGASFINVSMSTITSKWFGEDE 596

  Fly   742 RAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGDGNNSGTRIVNQLLTEMDGVEERKG--VYIL 804
            :.|||.|..|...:|.:||.||.||:..:|:..|: :.:..:|.|:.:|..||:..:.|  :.:|
plant   597 KNVRALFTLAAKVSPTIIFVDEVDSMLGQRTRVGE-HEAMRKIKNEFMTHWDGLMTKPGERILVL 660

  Fly   805 AATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGY 869
            ||||||..:|.||:|  |.:..:.||.|....|.:||:......|    .:::|..|:...||||
plant   661 AATNRPFDLDEAIIR--RFERRIMVGLPSIESREKILRTLLSKEK----TENLDFHELGQITEGY 719

  Fly   870 TGADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQH--FQEALQQLRPSVNEQDRK 924
            :|:|                       |.:||:.:.:  .:|.:||.|  :.:|:||
plant   720 SGSD-----------------------LKNLCITAAYRPVRELIQQER--LKDQERK 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	174/732 (24%)
		AAA	287..418	CDD:278434	28/148 (19%)
		P-loop_NTPase	679..>716	CDD:304359	18/37 (49%)
		AAA	699..830	CDD:278434	57/132 (43%)
AT5G52882	NP_001078747.1	P-loop_NTPase	515..>575	CDD:304359	29/60 (48%)
		AAA	552..686	CDD:214640	60/136 (44%)
		AAA	554..685	CDD:278434	58/133 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810