Protein Alignment smid and Pex1

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_001102690.1
• Gene: Pex1 / 500006
• RGDID: 1559939
• Length: 1283
• Species: Rattus norvegicus
• Alignment Length: 882
• Identity: 242/882 - (27%)
• Similarity: 364/882 - (41%)
• Gaps: 223/882 - (25%)

  Fly    83 SEDSEPPPTNSVMNNMMNSL--------YSQPRKPLAPKPISEPIDISSGDENEDDSNTKTTNGD 139
            |:.||......|:..:.|.|        :::..:||....:..|.|:           .|..|.:
  Rat   371 SDGSEEAAETCVLKVVWNGLEELKNATEFTKSLEPLHHGKVWIPADL-----------RKRLNIE 424

  Fly   140 GVAAAAAPPPPTPAVQGSALK-----RLMEEVPEIAVAA-------KKVAKPNTIHVSSSEAIQK 192
            ..|.....|..|..|...||:     .|..:|.|..|.|       :.......:.:|..|.| |
  Rat   425 MHAVVRITPLETTPVIPRALRLQPAENLPRDVSEEEVKAVFSSWLQESATTMFPLIISKQECI-K 488

  Fly   193 LHQVVGNRAKNLS--EDAVPRSKDHRNV----PGLYQQLH-QNQSRDRLRKFKRDLEVQHPTESF 250
            |....|.:..:||  .......:..|.|    |.|.|::. |......:.:...::::..|:.:.
  Rat   489 LEIKDGLKEFSLSIVHSQEKEKEQGRTVFVLSPILLQKISVQVLLEPMIGEHSEEIDILLPSLTL 553

  Fly   251 RDIGGMDSTLKELCEMLIHI-----KSPEFYFQLGLLPSRGLLLHGPPGCGKTFLARAISGQLKM 310
            ..:||:.|......|.:.|.     .|.:....:..|.:..||:.|..|.||:.||:||..:...
  Rat   554 SSLGGVSSLSVSAMEHITHSLLGRPLSRQLMALVAGLRNGALLITGGKGSGKSTLAKAICKEAHD 618

  Fly   311 PL---MEIPATELIGGISGESEERIREV-FDQAIGYSPCVLFIDEIDAIGGNRQWASKDMERRIV 371
            .|   :|:...:.:.|...||.::..|| |.:|....|.|:.:|::|.|.|.......:.....|
  Rat   619 ALDAHVEMVDCKALRGKRLESIQKALEVAFSEAAWRQPSVILLDDLDLIAGLPSTPEHEHSPEAV 683

  Fly   372 --SQLISSLDNLKANEF---GQSVVVIAATTRPDVLDPGL---RRIGRFDHEIAIHIPSRKERRE 428
              .:|..:|:|: ..||   |..|.:||.:.....|.|.|   :.:..|.....|..|.:::|.|
  Rat   684 QSQRLAHALNNM-IKEFVSMGSLVALIATSQLQHSLHPSLVSAQGVHTFQCIQHIQPPDQEQRCE 747

  Fly   429 IL------RIQCEGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAAS 487
            ||      ::.|: :|..|.|:...||:.|..:|..|...||.||
  Rat   748 ILHSVVKNKLGCD-ISKSPDLDLKCIAKETEAFVARDFTVLVDRA-------------------- 791

  Fly   488 EKNMTTVTLDDDEPSEDAGETPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKK 552
                                                                             
  Rat   792 ----------------------------------------------------------------- 791

  Fly   553 ATNGNSSIKSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNF 617
                                                        :.||.|..:
  Rat   792 --------------------------------------------IHSSLSRQQ------------ 800

  Fly   618 LDNPPEEFADPNFCLTLIDFVDAIKVMQPSAKREGFITVP-DTTWDDIGALEKIREELKLAVLAP 681
              ||..|    ...||..||..|::...|::.|...:..| |..||.||.|.::|:.|...:..|
  Rat   801 --NPTRE----GLTLTTADFQKALRGFLPASLRNVNLHKPRDLGWDKIGGLHEVRQILMDTIQLP 859

  Fly   682 VKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRA 746
            .||||:...|.:...:|:||.||||.||||||..:|.|:|:||||::||||::.|:|.||:|||.
  Rat   860 AKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVVARESGMNFISIQGPELLSKYIGASEQAVRD 924

  Fly   747 CFQRARNSAPCVIFFDEFDSLCPKRSDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPD 811
            .|.||:.:.||::|||||:|:.|:|  |.|......|:||||||::||||..:|||:||||:|||
  Rat   925 VFIRAQAAKPCILFFDEFESIAPRR--GHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPD 987

  Fly   812 IIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAG 876
            :||||:|||||||..:|...|:|..|.|||...:|:  .| |||||||..:|:.||.:|||||..
  Rat   988 LIDPALLRPGRLDKCVYCPPPDQVSRLEILTVLSKS--LP-LADDVDLQHVASVTESFTGADLKA 1049

  Fly   877 LVKQASMFSLRQSL------NNGDTNLDDLCVRSQHF 907
            |:..|.:.:|:..|      :.|.::..||.:.|..|
  Rat  1050 LLYNAQLEALQGRLLPGGLHDGGSSSDSDLSLSSMVF 1086

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	205/696 (29%)
Pex1	NP_001102690.1	PEX-2N	17..98	CDD:462730
		PEX-1N	104..179	CDD:462729
		NACHT	418..>750	CDD:444362	79/333 (24%)
		CDC48	<595..1060	CDD:273521	190/618 (31%)