Protein Alignment smid and Iqca1l

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_001019488.2
• Gene: Iqca1l / 499971
• RGDID: 1564789
• Length: 822
• Species: Rattus norvegicus
• Alignment Length: 781
• Identity: 165/781 - (21%)
• Similarity: 271/781 - (34%)
• Gaps: 194/781 - (24%)

  Fly   222 YQQLHQNQS-RDRLRKFKRDLEVQHPTESFRDIGGMDSTLKELCEMLIHIKSPEFYFQLGLLPSR 285
            |.||.|..: :.|.:.....|....|..|..::.||..|     |.||.::..|
  Rat   123 YFQLEQTSTMKARQQMLAEILARLEPLASQENLRGMSRT-----EALIIVQCAE----------- 171

  Fly   286 GLLLHGPPGCGKTFLARAISGQLKMPLM-EIPATELIGGISGESEERIREVFDQAIGYSPCVLFI 349
                            ||..|:|:...| ||...|       |.:.||||...|........:.|
  Rat   172 ----------------RARQGRLRATFMREIRKEE-------ERDRRIRENGRQKFSQDQGAIVI 213

  Fly   350 DEI--DAIGGNRQWASKDMERRIVSQLISSLDNLKANEFGQSVV-VIAATTRPDVLDPGLRRIGR 411
            .::  ..:...|....:.||...:..|.||....:.|...|:.| ..:..||....:...:....
  Rat   214 QKVWKGYLQRKRIEQDRRMEMEFIGMLPSSSQTTRQNALAQAFVGEESRRTRQVEKEEEFQEAIA 278

  Fly   412 FDHEIAIHI--PSRKER-REILR---IQCEGLS------VDPKL--NYDKIAELTPGYVGADLMA 462
            ..||.....  |..||| ::.:|   |:|..|:      .|...  :|...|:.||..|..:|.|
  Rat   279 KTHESLTETEGPDMKERMKDQIRQWFIECHALTGRFPDYPDEASGGSYLIFADKTPEQVRQELEA 343

  Fly   463 LV----------SRAASVAVKRRSMKKFRELHA--------------------ASEKNMTTV--- 494
            ..          ::......|.:..||.:|..|                    |..:..|::
  Rat   344 QAQENKKKEQEKNKDKVKEKKEKKKKKTKEEKAKKDPEVMFKVLPSKSIPVINAGHEEFTSIWKS 408

  Fly   495 TLDDDEPSEDAGETPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSS 559
            ..|:..||:....    ::..||..|..|.|.:|..|:..    :.|..:..:...::.|.
  Rat   409 RYDNKHPSQSFDS----ETLREEKRKQVEMEIRVQVDELM----RQELRNLRLAVDREETR---- 461

  Fly   560 IKSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYE----------PTLAEL 614
               |.|:|||...|             :..||..|:::....|.|..:|          ..|..|
  Rat   462 ---PLKSPKKKGGK-------------KSGKKKKEKDLTPDRSVDSLFEELVVIGLIKKSLLVTL 510

  Fly   615 TNFLDNPPEEFADPNFCLTLIDFVD-AIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKL-A 677
            .:::.:          ||.|...:. |.|:..||                   |..||:.:.| .
  Rat   511 NDYIGD----------CLYLGSTLTLANKIPMPS-------------------LFDIRQNIALYG 546

  Fly   678 VLAPVKYPEMLERLG-----LTAP--SGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNM 735
            ||          |||     ..||  ..:||.||.|.||.:|.:|:..|.|.|...:....:|..
  Rat   547 VL----------RLGSHDIHTMAPLVRSILLVGPSGMGKKMLVQAVCTETGANLFDLSPGNVMGK 601

  Fly   736 YVGE--SERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGDGNNSGTRIVNQLL--TEMDGVE 796
            |.|:  |:..:...|:.||...|.||:....:....|:....:......||...|:  |...|..
  Rat   602 YPGKNGSQLLMHIVFKVARVFQPSVIWIGNTEKTFYKKIPKEERRMDPKRIKKDLMRATRQLGPG 666

  Fly   797 ERKGVYILAATNRPDIID-PAILRPGRLDTILYVGFPEQSERTEILKATTKN-GKRPVLADDVDL 859
            :|  |.::..|.||.:.: ..:.|  ..:.||::..|:.:.|..:.|...:| |........:|:
  Rat   667 DR--VMLIGTTERPQLAEMKGLCR--FYERILFIPRPDYASRYVLWKRMIENQGIGVQQTQSLDI 727

  Fly   860 DEIAAQTEGYTGADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQLRPSVNEQDRK 924
            ..:|..::|||...:...::  |:.:.|:.|     .|....:.:..|...|.:|.|...|::..
  Rat   728 SALARVSDGYTPGHILQSIQ--SVLTERRLL-----QLTKKPLVASEFVVHLAKLDPVYREEEES 785

  Fly   925 I 925
            :
  Rat   786 L 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	159/760 (21%)
Iqca1l	NP_001019488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..378		7/39 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	457..484		10/46 (22%)
		P-loop containing Nucleoside Triphosphate Hydrolases	537..696	CDD:476819	46/172 (27%)