Protein Alignment smid and NSF

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_006169.2
• Gene: NSF / 4905
• HGNCID: 8016
• Length: 744
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 110/322 - (34%)
• Similarity: 174/322 - (54%)
• Gaps: 34/322 - (10%)

  Fly   650 REGFITVPDTTWD--DIGALEK-IREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTL 711
            |:..|. ||..::  .||.|:| ..:..:.|..:.|..||::|::|.....|:||.|||||||||
Human   205 RQSIIN-PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTL 268

  Fly   712 LAKAI-----ANEAGINFISVKGPELMNMYVGESERAVRACFQRAR--------NSAPCVIFFDE 763
            ||:.|     |.|..:    |.|||::|.||||||..:|..|..|.        ||...:|.|||
Human   269 LARQIGKMLNAREPKV----VNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDE 329

  Fly   764 FDSLCPKRSDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILY 828
            .|::|.:|............:|||||:::||||:...:.::..|||||:||.|:||||||:..:.
Human   330 IDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKME 394

  Fly   829 VGFPEQSERTEILKA-TTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSLNN 892
            :|.|::..|.:||.. |.:.....:|:.|||:.|:|.:|:.::||:|.|||:.|...::.:.: .
Human   395 IGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI-K 458

  Fly   893 GDTNL-------DDLCVRSQHFQEALQ-QLRPS--VNEQDRKIYDKLR-LKYAAPRVPTLND 943
            ..|.:       :.|.|....|..:|: .::|:  .|::|...|.... :|:..|....|:|
Human   459 ASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDD 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	106/310 (34%)
NSF	NP_006169.2	CDC48_N	6..83	CDD:215012
		CDC48_2	111..183	CDD:215011
		CDC48	159..>606	CDD:273521	110/322 (34%)
		RecA-like_NSF-SEC18_r1-like	219..395	CDD:410912	73/179 (41%)