DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment smid and nmd

DIOPT Version :9

Sequence 1:NP_523959.2 Gene:smid / 38824 FlyBaseID:FBgn0016983 Length:944 Species:Drosophila melanogaster
Sequence 2:NP_001285801.1 Gene:nmd / 44021 FlyBaseID:FBgn0005322 Length:369 Species:Drosophila melanogaster


Alignment Length:288 Identity:96/288 - (33%)
Similarity:155/288 - (53%) Gaps:42/288 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   648 AKREGF-----------------ITVP-DTT--WDDIGALEKIREELKLAVLAPVKYPEMLERLG 692
            |::|||                 :.|| |.|  |.||..|:.:.:||:.:|:.|:::.::.:...
  Fly    63 AEQEGFKLRGQEFSDYELMIASHLVVPADITVSWADIAGLDSVIQELRESVVLPIQHKDLFKHSK 127

  Fly   693 L-TAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAP 756
            | .||.||||.|||||||||:|||.|.|||:.||::....|.:.:.|||::...|.|..|....|
  Fly   128 LWQAPKGVLLHGPPGCGKTLIAKATAKEAGMRFINLDVAILTDKWYGESQKLTSAVFSLASRIEP 192

  Fly   757 CVIFFDEFDSLCPKRSDGGDGNNSGTRIVNQLLTEMDGVEERKG--VYILAATNRPDIIDPAILR 819
            |:||.||.||..  ||...:.:.:...:..|.:...||:.....  |.::.|||||..:|.||:|
  Fly   193 CIIFIDEIDSFL--RSRNMNDHEATAMMKTQFMMLWDGLSTNANSTVIVMGATNRPQDLDKAIVR 255

  Fly   820 PGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMF 884
              |:....::|.|.:::|.:|||...::.:   ::.||||:.::..|.|::|:||..:.:.||::
  Fly   256 --RMPAQFHIGLPSETQRKDILKLILQSEE---VSQDVDLNRLSKLTNGFSGSDLREMCRNASVY 315

  Fly   885 SLRQSL------------NNGDTNLDDL 900
            .:||.:            ||....:|||
  Fly   316 RMRQLITSRDPSATALDRNNVRITMDDL 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
smidNP_523959.2 Nucleolin_bd 2..71 CDD:293330
SpoVK 271..919 CDD:223540 96/288 (33%)
AAA 287..418 CDD:278434
P-loop_NTPase 679..>716 CDD:304359 19/37 (51%)
AAA 699..830 CDD:278434 52/132 (39%)
nmdNP_001285801.1 AAA 132..266 CDD:214640 55/137 (40%)
AAA 135..265 CDD:278434 52/133 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0464
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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