Protein Alignment smid and CG16789

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Alignment Length: 892
• Identity: 170/892 - (19%)
• Similarity: 297/892 - (33%)
• Gaps: 245/892 - (27%)

  Fly   126 ENEDDSNTKTTNGDGVAAAAAPPPPTPAVQGS---------ALKRLMEEVPEIAVAAKKVAKPNT 181
            :::|...|..|....|.:.||.......:|.|         .|...:|:|.:           |.
  Fly    28 QHQDVETTVATMNAAVGSVAADADAKALLQSSLYEFYLRYICLSNRLEDVYD-----------NM 81

  Fly   182 IHVSSSEAIQKLHQVVGNRAKNLSEDAVPRSKDHRNVPGLYQQLHQNQSRDRLRKFKRDLEVQHP 246
            |.....:.::||......|...|..|.|       |: .|.:..:.::..:|||....:.|::.|
  Fly    82 IQPQKRQLVRKLLDACLGRVVELKHDLV-------NI-DLMEFSYNDEVVERLRLTPMETELRIP 138

  Fly   247 ----TESFRDIGGMDSTLKELCEMLIHIKSPEF--YFQLGLLPSRGLLLHGPPGCGKTFLARAIS 305
                .|..:::.....|:.|:...|..::..|.  .....:...|.|.:|          .||..
  Fly   139 RYFLRERQQELEFRKKTMHEILTKLGWLEEHELEETVTTEIEAIRMLQMH----------ERARQ 193

  Fly   306 GQLKMPLMEIPATEL-IGGISGESEERI-REVFDQAIGYSPCVLFIDEIDAIGGNRQWASKDMER 368
            |:|:...|:    |: |....|:||||. :|..|..:           :.|:...:.|.. ...|
  Fly   194 GRLRAHFMK----EIRILKEKGKSEERTEKERSDSGL-----------LAAMKIQKMWRG-HTAR 242

  Fly   369 RIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREILRIQ 433
            ||.          :..:..:.:::......|.|:                     |||.|.|.
  Fly   243 RIT----------RRRKMEEMILIGMLPPPPAVV---------------------KERAEKLE-- 274

  Fly   434 CEGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMK-KFRELHAASEK----NMTT 493
                    ||.:::.......:.|.:.          ..::.::| :.|..|.||.|    :...
  Fly   275 --------KLQHNEKRYQAQAFYGKEF----------EERQNALKEEIRAKHGASMKEDIADEIR 321

  Fly   494 VTLDD---------DEPSEDAGET----PVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSP 545
            ..:.|         |.||||.|.:    ..|.::.|.:...|.:.::       |.|.|.:..||
  Fly   322 AWVKDCYDKTGKLPDFPSEDQGGSLHIFSRPGTESEHSRSSARSSKE-------SRKTKDKSKSP 379

  Fly   546 NIETPKKATNGNSSIKSPQKTPKKSAEKPTDAAMDV--------DNVAPEEPKKAVEQEV-DSSS 601
                   |.:|:.::...|.........|:....|:        |....::....:.|.. :...
  Fly   380 -------ARSGDLNVNENQDEEVSFQPAPSVCLPDIRAEIDLFNDTWRDKDETGVLSQAAYEDMI 437

  Fly   602 SNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDFVDAIKVMQPS-----------AKREGFIT 655
            .:|:|.|..| |....:|:...:.      :.|:......||.:.|           .|:|..:|
  Fly   438 YSDKYQEVEL-EFRRAVDDVMRQE------IELLQTAVGKKVKKSSKKTRRSGKKSKKKKEKDLT 495

  Fly   656 VPDTTWDDIGALEKIREELKLAVLAPVKYPE-----------MLERLGLTAPS------------ 697
             ||.|      .|.:.|||....:.. ||||           :..|:| |.||
  Fly   496 -PDRT------TESLYEELVTNGIIR-KYPELRLKQFLGDKALTARIG-TNPSPGDIRQILTEYC 551

  Fly   698 -----------------GVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESE--RA 743
                             .:||.||.|.||..|..||..|.|.....:....::..|.|:|.  ..
  Fly   552 ILPLGSDAIHNCTPLIRSILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYPGKSGLIML 616

  Fly   744 VRACFQRARNSAPCVIFFDE----FDSLCPK--RSDGGDGNNSGTRIVNQLLTEMDGVEERKGVY 802
            :....:.:|...|.|||..:    |....||  |:|       ..|:...|...:..:.....|.
  Fly   617 IHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTDRTD-------PKRLKKDLPKLIKNIAPEDRVV 674

  Fly   803 ILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTE 867
            .:..:|.|...|..:|: ...:..:|:..|:....:...|....:....:  .::|...:|..::
  Fly   675 FIGTSNLPWEADQKLLQ-SVYNRFIYIPRPDYGAMSHAWKTLLHDYSGGI--SNLDTSAMAKISD 736

  Fly   868 GYTGADLAGLVKQA----SMFSLR-QSLNNGDTNLDDLCVRSQHFQE 909
            |||...:...:|:.    ....|| |.|.|.:. ::.||.|...::|
  Fly   737 GYTIGSIDACLKEVMTCKRKLQLRTQPLTNAEL-INVLCSRDPVYRE 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	146/767 (19%)
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	41/252 (16%)
		SpoVK	443..773	CDD:440232	73/356 (21%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	32/165 (19%)