DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment smid and trip13

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_956876.1	Gene:	trip13 / 393554	ZFINID:	ZDB-GENE-040426-1488	Length:	424	Species:	Danio rerio

Alignment Length:	336	Identity:	82/336 - (24%)
Similarity:	132/336 - (39%)	Gaps:	67/336 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   579 MDVDN-----------VAPEEPKKAVEQEVDS-----SSSNDEYYEPTLAELTNFLDNPPEEFAD 627
            ||.||           :|.....|.|:.:|.:     .:.||:  .|:...|     ...||.:.
Zfish    56 MDFDNEFLTKNVESVTIADVTGPKLVDLKVHNLCIHIFTLNDD--SPSTLNL-----EEEEELSA 113

  Fly   628 PNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLERLG 692
            .|..|.            |:.:..|       .|:.:...|.|:.:|...|...:.:.:......
Zfish   114 ANLWLL------------PAVEFHG-------VWESLIYEEGIKTQLLDYVSTTIFFSDKNVDSN 159

  Fly   693 LTAPSG-VLLCGPPGCGKTLLAKAIANEAGI---------NFISVKGPELMNMYVGESERAVRAC 747
            |.|.:. |||.||||.|||.|.|.:|.:..|         .|:.:....|.:.:..||.:.|...
Zfish   160 LIAWNRVVLLHGPPGTGKTSLCKGLAQKLSIRLSDRYAHSQFVEINSHSLFSKWFSESGKLVTKM 224

  Fly   748 FQRAR-----NSAPCVIFFDEFDSLCPKRS--DGGDGNNSGTRIVNQLLTEMDGVEERKGVYILA 805
            ||:.:     ..|...:..||.:||...||  ..|...:...|:||.:||::|.::....|.||.
Zfish   225 FQKIQELIDDKDALVFVLIDEVESLTAARSAAQAGTEPSDAIRVVNSVLTQLDQIKRHPNVVILT 289

  Fly   806 ATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEI-LKATTKNGKRPVL---ADDVDLDEIAAQT 866
            .:|..:.||.|.:  .|.|...|:|.|.......| |.:..:..||.::   ...|.|:|:  :|
Zfish   290 TSNVTEKIDLAFV--DRADIKQYIGPPSAKAIFNIYLSSLEELMKRQIIYPRQQLVSLEEL--ET 350

  Fly   867 EGYTGADLAGL 877
            ..:..:|:..|
Zfish   351 MNFMESDVTRL 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	82/336 (24%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	14/37 (38%)
		AAA	699..830	CDD:278434	45/146 (31%)
trip13	NP_956876.1	AAA	164..314	CDD:214640	46/151 (30%)
trip13	NP_956876.1	AAA	167..312	CDD:278434	45/146 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900