Protein Alignment smid and Pex6

DIOPT Version :9

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 1017
• Identity: 240/1017 - (23%)
• Similarity: 405/1017 - (39%)
• Gaps: 299/1017 - (29%)

  Fly    35 MTRELMQKYPEYSRRKF--GPFRQLVHQAFSIISESYNLDKVSSSEEDCVSEDSEPPPTNSVMNN 97
            :|..:..:|.:|.:.||  .|....::... |.:|....:.:..:.::.....:|.|..|.|
  Fly    64 LTYAVYWRYAKYYKGKFLLTPIPNRLYDLL-IKNEQIKSEHLVFASQEVYENYAESPDVNFV--- 124

  Fly    98 MMNSLYSQPRKPLAPKPISEPIDISSGDENEDDSNTKTTNGDGVAAAAAPPPPTPAVQGSALKRL 162
               :|..:.|:....||::           .|:.|...|                     .:|::
  Fly   125 ---NLVIRGRRVRIGKPLA-----------SDEGNMTQT---------------------VIKQM 154

  Fly   163 MEEVPEIAVAAKKVA---KPNTIHVSSSEAIQKLHQVVGN-----RAKNLSEDAVPRSKDHRNVP 219
            ::|.|...||....|   :||.::|..:        ..||     :.::.....|....|.:.:|
  Fly   155 LQEAPHTIVAQILPAAQCQPNCLYVQEN--------FYGNILDRFQIRSNCWVQVEHFADEQTIP 211

  Fly   220 GLYQQLHQNQSRDR-----------LRKFKRDLEVQHPTESFR-----DIGG---------MDST 259
            |:..:.|.....|.           |..:.....:.|...::|     ::.|         :.:.
  Fly   212 GIATKAHVYLVADPHELPAELTEVILSNYFNTPRLMHRGHTYRIEVNAELVGTATYAHYYLIFAH 276

  Fly   260 LKELCEMLIHI--KSPEFYFQL-----------------------------------GL------ 281
            |:.:....||:  |..||..|.                                   ||
  Fly   277 LRHVHLKCIHLETKGSEFELQAIVAKNFSNLVQVPASHSFLPRQVLDSMAIVENYPSGLRKPYKL 341

  Fly   282 --------LPSRG-----------LLLHGPPGCGKTFLARAISGQLKMPLMEIPATELIGGISGE 327
                    ||.:.           .||.|..|.||:.|..|::.:|.|.:......|::..:...
  Fly   342 LRSSVDAFLPKKSACLSSKHIFPVFLLQGERGSGKSKLVSAVAQELGMHIYGADCAEIVSQVPSH 406

  Fly   328 SEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKDMERRIVSQLISSLDNLKANEFGQSVVV 392
            :|.:::.||.::....|.::.....:..|.:.: .::|:  |::|.....:..|...:....:||
  Fly   407 TEMKLKAVFAKSQVCEPLMICFHNFEIFGIDNE-GNEDL--RLLSAFHVQVQELFNRDRKHPIVV 468

  Fly   393 IAATTRPDVLDPGLRRI--GRFDHEIAIHIPSRKERREILRIQCEGLSVDPKLNYDKIAELTPGY 455
            :|.|:     |..|:.:  |.|...|.|.:||::||.||||......:.:..:...|..|..|
  Fly   469 VALTS-----DRHLKPMIQGLFLEIINIDMPSKEERFEILRWMHVRETFNDIIYNQKAIEQLP-- 526

  Fly   456 VGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVTLDDDEPSEDAGETPVPDSKGEETAK 520
                   |.||........|....:||            ||:                    ..:
  Fly   527 -------LFSRENQSQFMPRISPSWRE------------TLN--------------------VLQ 552

  Fly   521 DAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSIKSPQKTPKKSAEKPTDAAMDVDNVA 585
            |..|              ||:|....                             |..:..||
  Fly   553 DVAA--------------KSQGFLLG-----------------------------DLQLLYDN-- 572

  Fly   586 PEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDFVDAIKVMQPS-AK 649
                  ||..::.:....      |..::::|..|             |.|       ||.| |.
  Fly   573 ------AVRMKIRNRLGR------TTLDMSHFAKN-------------LTD-------MQSSFAD 605

  Fly   650 REGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEM----LERLGLTAPSGVLLCGPPGCGKT 710
            ..|...||...|.|||.|.|:::|::.::..|:|:..:    |.|      ||:||.||||.|||
  Fly   606 SLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMGKNLRR------SGILLYGPPGTGKT 664

  Fly   711 LLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGG 775
            |:|||:|.|..::|:||:||||:|||||:||:.||..|.|||::||||:|.||.|||.|.|...|
  Fly   665 LVAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAG 729

  Fly   776 DGNNSGTRIVNQLLTEMDGVEE---RKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSE- 836
            |......|:|:|||.||||:.:   .|.::|||||||||:||||:|||||.|.:.|||....:|
  Fly   730 DSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYVGPCSTAED 794

  Fly   837 RTEILKATTKNGKRPVLADDVDLDEIAAQTEG-YTGADLAGLVKQASMFSLRQSLNN------GD 894
            :..:|:|.|   :|..|...||:::||.:.:. .:||||..:...|.:.::|::::.      .:
  Fly   795 KAAVLRAQT---QRFALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRRTIDGHLSGTISE 856

  Fly   895 TNL--DDLCVRSQHFQEALQQLRPSVNEQDRKIYDKLRLKYA 934
            ..|  :::.|:.:.|.::..:..||::.:|.:.::.|:..|:
  Fly   857 KELVPENVIVQEEDFTKSFNKFVPSISAKDLEYFNNLKASYS 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330	8/37 (22%)
		SpoVK	271..919	CDD:223540	194/727 (27%)
		AAA	287..418	CDD:278434	29/132 (22%)
		P-loop_NTPase	679..>716	CDD:304359	18/40 (45%)
		AAA	699..830	CDD:278434	79/133 (59%)
Pex6	NP_001027403.2	SpoVK	367..847	CDD:223540	181/614 (29%)
		P-loop_NTPase	367..492	CDD:304359	29/132 (22%)
		AAA	653..787	CDD:278434	79/133 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445202
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23077
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940