DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and atad1a

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_001004640.1	Gene:	atad1a / 368672	ZFINID:	ZDB-GENE-030616-593	Length:	380	Species:	Danio rerio

Alignment Length:	365	Identity:	115/365 - (31%)
Similarity:	180/365 - (49%)	Gaps:	72/365 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   578 AMDVDNVAPEEPKKAVEQ-----EVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDF 637
            |:|.......:.||..||     .|:..|..:  ||..:|.|          ..||.
Zfish    43 ALDPTQKQKSQAKKRAEQLMKQIGVEGVSLTE--YEMNIATL----------LVDPR-------- 87

  Fly   638 VDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEML--ERLGLTAPSGVL 700
              :|||                ||.|:..|::|..|::..|:.|.:...:.  .:| |..|.|||
Zfish    88 --SIKV----------------TWRDVAGLDEIISEMQDTVILPFQKRHLFSGSKL-LQPPKGVL 133

  Fly   701 LCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFD 765
            |.|||||||||:|||.|..:|..||:::...|.:.:.|||::...|.|..|....||:||.||.|
Zfish   134 LYGPPGCGKTLIAKATAKASGCRFINLQASTLTDKWYGESQKLTAAVFSLAVKIQPCIIFLDEID 198

  Fly   766 SLCPKRSDGGDGNNSGTRIVN-QLLTEMDGVE--ERKGVYILAATNRPDIIDPAILRPGRLDTIL 827
            |....||   ..::..|.::. |.::..||::  |...|.::.|||||..:|.||||  |:.|..
Zfish   199 SFLRNRS---SMDHEATAMMKAQFMSLWDGLDTGENSQVMVMGATNRPQDVDAAILR--RMPTAF 258

  Fly   828 YVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSLNN 892
            :||.|..::|.|||:... :|:.  |::.::|.|||:|:|||:|:||..|.:.|:|:.:|.
Zfish   259 HVGLPNAAQREEILRLIL-SGEN--LSNAINLKEIASQSEGYSGSDLKELCRDAAMYRVRD---- 316

  Fly   893 GDTNLDDLCVRSQHFQEALQQLRPSVNEQDRKIYDKLRLK 932
                    .||.|..::..||.:  ::|::..: |..:|:
Zfish   317 --------YVRKQQMKQIAQQFQ--LDEEEEHV-DSRQLR 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	112/350 (32%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	19/38 (50%)
		AAA	699..830	CDD:278434	54/133 (41%)
atad1a	NP_001004640.1	AAA	128..254	CDD:214640	54/130 (42%)
atad1a	NP_001004640.1	AAA	132..262	CDD:278434	55/134 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900