DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and atad1b

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_001019592.1	Gene:	atad1b / 368412	ZFINID:	ZDB-GENE-030616-44	Length:	362	Species:	Danio rerio

Alignment Length:	383	Identity:	116/383 - (30%)
Similarity:	174/383 - (45%)	Gaps:	89/383 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   563 PQKTPKKSAEKPTDAAM---DVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEE 624
            |.:..|..|:|..:..|   .|.||...|                  ||.::|          ..
Zfish    47 PTRKQKVEAQKQAEKLMRQIGVQNVKLSE------------------YEMSIA----------AH 83

  Fly   625 FADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLE 689
            ..||   ||:                       ..||.||..|:::..|||..|:.|::...:.|
Zfish    84 LVDP---LTM-----------------------QITWYDIAGLDEVITELKDTVILPIQKRHLFE 122

  Fly   690 --RLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRAR 752
              || |..|.||||.|||||||||:|||.|.|||..||:::...|.:.:.|||::...|.|..|.
Zfish   123 GSRL-LQPPKGVLLYGPPGCGKTLIAKATAKEAGFRFINLQPSTLTDKWYGESQKLAAAVFSLAI 186

  Fly   753 NSAPCVIFFDEFDSLCPKRSDGGDGNNSGTRIVN-QLLTEMDGVEERKG--VYILAATNRPDIID 814
            ...|.:||.||.||....||   ..::..|.::. |.::..||::....  |.|:.|||||..:|
Zfish   187 KLQPSIIFIDEIDSFLRNRS---SSDHEATAMMKAQFMSLWDGLDTDYNCQVIIMGATNRPQDLD 248

  Fly   815 PAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVK 879
            .||||  |:.|..::..|...:|.:|||...:|..   :...|:|.|||.||:|::|:||..:.:
Zfish   249 SAILR--RMPTRFHINQPNARQRKDILKLILENEN---VESAVELSEIAKQTDGFSGSDLREMCR 308

  Fly   880 QASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQ--LRPSVNEQDRKIYDKLRLKYAA 935
            .|::                ||||....||:.::  :||...|..::..:|::...:|
Zfish   309 DAAL----------------LCVRDFVHQESPEEDFIRPIRQEDLQRAIEKMKKSKSA 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	113/365 (31%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	21/38 (55%)
		AAA	699..830	CDD:278434	55/133 (41%)
atad1b	NP_001019592.1	AAA	129..258	CDD:214640	56/133 (42%)
atad1b	NP_001019592.1	AAA	133..261	CDD:278434	55/132 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810