Protein Alignment smid and CG5776

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Alignment Length: 860
• Identity: 241/860 - (28%)
• Similarity: 378/860 - (43%)
• Gaps: 251/860 - (29%)

  Fly   110 LAPKPISEPIDISSGDENEDDSNTKTTN-GDGVAAAAAPPPPTPAVQGSALKRLMEEVPEIAVAA 173
            |.|..::....||....|..:::.|:.. .|.:|               .|||.|        ..
  Fly   154 LHPSRLTAAASISLKHVNTTETSLKSVQLQDAIA---------------LLKRDM--------VN 195

  Fly   174 KKVAKPNTIHV-----SSSEAIQKLHQVVGNRAKNLSEDAVPR--------SKDHRNVPGLYQQL 225
            :...|.:.||:     |.:..:::....|......||.|:.|.        :|.|.......||.
  Fly   196 RVFYKDSLIHMNFFNKSLTFRLERWQSTVEEALAGLSLDSKPLQFIQVTNVTKLHLITDDANQQE 260

  Fly   226 HQNQSRDRLRKFKRDLEVQHPTESFRDIGGMDSTLKELCEMLIHIKSPEFYFQLGLLP-----SR 285
            .:.:...|:.|.:              |||:|..| :|.|     :|.|:......||     ||
  Fly   261 EEQKISHRITKCQ--------------IGGLDRQL-QLVE-----ESMEYALGFRTLPAGLRVSR 305

  Fly   286 GLLLHGPPGCGKTFLARAI------SGQLKMPLMEIPATELIGGISGESEERIREVFDQAIGY-- 342
            ||||:|..||||:.:..|:      ..|..:.|:.|.:.|:.....||:|:::..:|::|..:
  Fly   306 GLLLYGATGCGKSMVLEAMCAVAEERSQGHVQLIRINSGEVYSKFLGETEQKLGAIFERAYNHYP 370

  Fly   343 SPCVLFIDEIDAIGGNRQWASKDMERRIVSQLISSLDNLKANE--FGQSVVVIAATTRPDVLDPG 405
            .|.:|.|:::..:...::  :.|:.:|:....:|.||.|.:..  .|....|:|.:::.|.|.|.
  Fly   371 HPTLLLIEDVHNLCPKQE--NSDLVKRVSLAFLSLLDQLSSPSQLKGSKTFVLATSSQIDTLHPS 433

  Fly   406 LRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKLN---YDKIAELTPGYVGADLMALVSRA 467
            :||.||.|:|:.:..||.:.|.||:|  |...||:.:|:   .:.:|.:|.|||||||..||..|
  Fly   434 IRRAGRLDNEVELGAPSSQARLEIVR--CLIKSVEHQLSDEEVEHVASITHGYVGADLANLVYAA 496

  Fly   468 ASVAVKRRSMKKFRELHAASEKNMTTVTLDDDEPSEDAGETPVPDSKGEETAKDAEAEQKVDGDK 532
            ...|
  Fly   497 MLQA------------------------------------------------------------- 500

  Fly   533 ETSAKDKSEGDSPNIETPKKATNGNSSIKSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEV 597
                       .||                |.:.|...|
  Fly   501 -----------QPN----------------PLQMPHLQA-------------------------- 512

  Fly   598 DSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWD 662
                                                      |:..::|||.||..|..|:..|.
  Fly   513 ------------------------------------------ALTRIKPSAMREVLIECPNVQWS 535

  Fly   663 DIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISV 727
            |||...::|..::.|:..|:.:.:..:|||:..|.|:|:.|||||.||::|||:|.|:.:||:|:
  Fly   536 DIGGQSELRLAMQQAIEWPLLHADKFQRLGIKPPRGILMFGPPGCSKTMIAKALATESKLNFLSI 600

  Fly   728 KGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGDGNNSGT----RIVNQL 788
            |||||.:|:|||||||||..|::||..||.::||||.|::..:||: |||::||:    |::.||
  Fly   601 KGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGERSE-GDGSSSGSSVKERVLTQL 664

  Fly   789 LTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVL 853
            |||:||||..:.|.|:|||||||:||.|:|||||:|.|||||.|:...|.||||  .|....|:
  Fly   665 LTELDGVEALQNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQCEARREILK--IKLRAMPI- 726

  Fly   854 ADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQLRPSV 918
            ::|||::::...||||:||::..:..:|::.:|.||....|....|       |:.||:.:.|..
  Fly   727 SNDVDMEKLVQLTEGYSGAEIQAVCHEAALRALEQSFEAEDVKWTD-------FEHALKAVPPRT 784

  Fly   919 NEQDRKIY-DKLRLK 932
            :.:..|:| |.|:.|
  Fly   785 SPELLKLYEDYLKRK 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	214/714 (30%)
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	233/827 (28%)