Protein Alignment smid and Fign

DIOPT Version :10

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Alignment Length: 584
• Identity: 154/584 - (26%)
• Similarity: 244/584 - (41%)
• Gaps: 118/584 - (20%)

  Fly   362 ASKDMERRIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKER 426
            |.||...|:  |...|::........:.:.:...|.|      |:...|     ....:|    .
  Fly    30 ALKDHHARL--QACESMEKAMKERCQKKITMSRRTKR------GITHAG-----YLFEMP----H 77

  Fly   427 REILRIQCEGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASV-----AVKRRSMKKFRELHAA 486
            ..:...:|.|.       |:...:..  ...:||.|.....:|.     |||.|...:|.|
  Fly    78 NSVFEPECRGF-------YESCQQTE--MASSDLQAPALEVSSTYPVQQAVKSRPEGQFPE---- 129

  Fly   487 SEKNMTTVTLDDDEPSEDAGETPVPDSKGEETAKDAEAEQKV-DGDKETSAKDKSEGDS-PN--I 547
             .:|.:|..:|..:.|   .|:......|..||:    ||.: |..|:.:.:..||.|: |.  :
  Fly   130 -SRNNSTKKIDAQQYS---SESSSQSGFGFRTAR----EQLIMDELKKKNRQATSEVDAVPTGMM 186

  Fly   548 ETPKKATNGNSSIKSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLA 612
            ...||...|..::.|...:|                         |.|..:|:||......|.||
  Fly   187 NFRKKTLGGKRTVSSNFVSP-------------------------VAQNDNSTSSRSSSIPPALA 226

  Fly   613 ELTNFLDNPPEEFADPNFCLTLIDFV--DAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELK 675
            .|.:                .::|.:  :::...:|.|            |:||..||..:....
  Fly   227 HLDS----------------KMVDHILGESMHDFKPVA------------WEDIAGLESAKSTFL 263

  Fly   676 LAVLAPVKYPEMLERLGLTA-PSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGE 739
            .|::.|::.|::.  .|:.. |.||||.||||.||||:||:||::|...|.|:....|.:.:||:
  Fly   264 EAIIMPLRRPDLF--TGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGD 326

  Fly   740 SERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGDGNNSGTRIVNQLLTEMDGV--EERKGVY 802
            :|:.|:..|..|....|.:||.||.|||..|||  .:.|.|..|:.|:.|..:||.  .|...|.
  Fly   327 AEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRS--ANENESTLRLKNEFLIHLDGAASNEEIRVL 389

  Fly   803 ILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTE 867
            ::.|||||..:|.|:.|  |....|||..|.:..|.:|::......|..:  |...:.|:|..|:
  Fly   390 VIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQKIIEKLIHQVKHNL--DVRQVIELAELTD 450

  Fly   868 GYTGADLAGLVKQASMFSLRQSLNNGDTNLDDL----CVRSQHFQEALQQLRPSVNEQDRKIYD 927
            ||:|||:..|.:.|||..|| ||......:.:.    .|....|::||:.:..||:.:|.|.::
  Fly   451 GYSGADVDTLCRYASMAPLR-SLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDCKQFE 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:465247
		CDC48	<242..933	CDD:273521	154/584 (26%)
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	6/21 (29%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	69/218 (32%)
		AAA_lid_3	444..495	CDD:465537	18/51 (35%)
		Vps4_C	<480..520	CDD:462762	8/34 (24%)