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Protein Alignment smid and vcp

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_958889.1	Gene:	vcp / 327197	ZFINID:	ZDB-GENE-030131-5408	Length:	806	Species:	Danio rerio

Alignment Length:	709	Identity:	251/709 - (35%)
Similarity:	367/709 - (51%)	Gaps:	161/709 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 KRDLEVQHPTE-SFRDIGGMDSTLKELCEML-IHIKSPEFYFQLGLLPSRGLLLHGPPGCGKTFL 300
            ||:.|.:...| .:.||||:...|.::.||: :.::.|..:..:|:.|.||:||:||||.|||.:
Zfish   190 KREDEEESLNEVGYDDIGGVRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLI 254

  Fly   301 ARAISGQLKMPLMEIPATELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKD 365
            |||::.:.......|...|::..::||||..:|:.|::|...:|.::||||:|||...|:....:
Zfish   255 ARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGE 319

  Fly   366 MERRIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREIL 430
            :||||||||::.:|.||..   ..|:|:|||.||:.:||.|||.||||.|:.|.||....|.|||
Zfish   320 VERRIVSQLLTLMDGLKQR---AHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEIL 381

  Fly   431 RIQCEGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVT 495
            :|..:.:.:...::.:::|..|.|:|||||.||.|.||..|::               |.|..:.
Zfish   382 QIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIR---------------KKMDLID 431

  Fly   496 LDDDEPSEDAGETPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSI 560
            |:|
Zfish   432 LED-------------------------------------------------------------- 434

  Fly   561 KSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEF 625
                                              :.:|             ||:.|.|
Zfish   435 ----------------------------------ETID-------------AEVMNSL------- 445

  Fly   626 ADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLER 690
                 .:|:.||..|:....|||.||..:.||:.||:|||.|:.::.||:..|..||::|:...:
Zfish   446 -----AVTMDDFRWALSQSNPSALRETVVEVPNITWEDIGGLDDVKRELQELVQYPVEHPDKFLK 505

  Fly   691 LGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSA 755
            .|:|...|||..|||||||||||||||||...||||:|||||:.|:.||||..||..|.:||.:|
Zfish   506 FGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAA 570

  Fly   756 PCVIFFDEFDSLCPKRSDG-GDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILR 819
            |||:||||.||:...|... |||..:..|::||:||||||:..:|.|:|:.||||||||||||||
Zfish   571 PCVLFFDELDSIAKARGGNVGDGGGAADRVINQILTEMDGMSSKKNVFIIGATNRPDIIDPAILR 635

  Fly   820 PGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMF 884
            |||||.::|:..|::..|..||||..:  |.|: :.|||||.:|..|.|::||||..:.::|...
Zfish   636 PGRLDQLIYIPLPDEKSRIAILKANLR--KSPI-SKDVDLDFLAKMTNGFSGADLTEICQRACKL 697

  Fly   885 SLRQSLNNG--------------DTNLDDLC--VRSQHFQEALQQLRPSVNEQDRKIYD 927
            ::|:|:.|.              :...||..  :|..||:||::..|.||::.|.:.|:
Zfish   698 AIRESIENEIRRERERQTNPSAMEVEEDDPVPEIRKDHFEEAMRFARRSVSDNDIRKYE 756

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.