DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and psmc6

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_001003832.1	Gene:	psmc6 / 321585	ZFINID:	ZDB-GENE-030131-304	Length:	389	Species:	Danio rerio

Alignment Length:	452	Identity:	129/452 - (28%)
Similarity:	208/452 - (46%)	Gaps:	104/452 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 KG-EETAKDAEAEQKVDGD--------KE-TSAKDKSEGDSPNIETP-----------------K 551
            || ::..|.....:::||.        || |...:|||.|...:::.                 .
Zfish     7 KGLQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIV 71

  Fly   552 KATNGNSSIKSPQKTPKKSAEKP-TDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELT 615
            |||||...:...::...||..|| |..|:|:..:.   ..:.:.:|||....|..:.:|
Zfish    72 KATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLT---IMRYLPREVDPLVYNMSHEDP------ 127

  Fly   616 NFLDNPPEEFADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLA 680
                                                     ...::.:||.|.:...||:..:..
Zfish   128 -----------------------------------------GSVSYSEIGGLSEQIRELREVIEL 151

  Fly   681 PVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVR 745
            |:..||:.:|:|:..|.|.||.||||.||||||:|:|::...||:.|....:::.|:|||.|.:|
Zfish   152 PLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIR 216

  Fly   746 ACFQRARNSAPCVIFFDEFDSLCPKR-SDGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNR 809
            ..|..||:..||:||.||.|::..:| |:|...:....|.:.:||.:|||.:....|.::.||||
Zfish   217 EMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNR 281

  Fly   810 PDIIDPAILRPGRLDTILYVGFPEQSERTEILK----ATTKNGKRPVLADDVDLDEIAAQTEGYT 870
            ||.:|||:|||||||..:::..|.:..|.:|||    ..||:|       |:|.:.|...::|:.
Zfish   282 PDTLDPALLRPGRLDRKIHIELPNEQARLDILKIHSGPITKHG-------DIDYEAIVKLSDGFN 339

  Fly   871 GADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQLRPSVNEQDRKIYDKLRLK 932
            ||||..:..:|.||::|         .|...|..:.|.:|::::..|     :|:..||..|
Zfish   340 GADLRNVCTEAGMFAIR---------ADHEYVTQEDFMKAVRKVADS-----KKLESKLDYK 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	125/437 (29%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	19/36 (53%)
		AAA	699..830	CDD:278434	59/131 (45%)
psmc6	NP_001003832.1	RPT1	1..387	CDD:224143	128/450 (28%)
psmc6	NP_001003832.1	AAA	171..303	CDD:278434	59/131 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910