DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and Trip13

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_001011930.1	Gene:	Trip13 / 292206	RGDID:	1308516	Length:	432	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	68/273 - (24%)
Similarity:	115/273 - (42%)	Gaps:	50/273 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   646 PSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEM-LERLGLTAPSGVLLCGPPGCGK 709
            |:|:..|.       ||.:....:::..|...|:..:.:.:. ::...:|....|||.||||.||
  Rat   128 PAAEFHGL-------WDSLVYDVEVKSHLLDYVMTTLLFSDKNVDSNLITWNRVVLLHGPPGTGK 185

  Fly   710 TLLAKAIANEAGI---------NFISVKGPELMNMYVGESERAVRACFQRARN-----SAPCVIF 760
            |.|.||:|.:..|         ..|.:....|.:.:..||.:.|...||:.::     .|...:.
  Rat   186 TSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVL 250

  Fly   761 FDEFDSLCPKRS--DGGDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRL 823
            .||.:||...|:  ..|...:...|:||.:||::|.::....|.||..:|..:.||.|.:  .|.
  Rat   251 IDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFV--DRA 313

  Fly   824 DTILYVGFPEQ--------SERTEILKATTKNGKRPVLA-----------DDVD-----LDEIAA 864
            |...|:|.|..        |...|::|......::.:|.           ::|.     |.||:.
  Rat   314 DIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISR 378

  Fly   865 QTEGYTGADLAGL 877
            ::||.:|..|..|
  Rat   379 KSEGLSGRVLRKL 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	68/273 (25%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	13/37 (35%)
		AAA	699..830	CDD:278434	45/146 (31%)
Trip13	NP_001011930.1	RecA-like_Pch2-like	121..319	CDD:410916	52/199 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900