Protein Alignment smid and lex-1

DIOPT Version :9

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_502289.2
• Gene: lex-1 / 178146
• WormBaseID: WBGene00008682
• Length: 1291
• Species: Caenorhabditis elegans
• Alignment Length: 670
• Identity: 183/670 - (27%)
• Similarity: 285/670 - (42%)
• Gaps: 134/670 - (20%)

  Fly   322 GGISGESEER----------IREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKDMERRIVSQLIS 376
            ||:.|....|          ..|.:.:||.        .|.|......:.:|..|..|  .|::.
 Worm    46 GGVDGNGYTRSGRKINHNRYYEEEYHEAIS--------SEEDERRYRTRRSSNSMTYR--QQVMQ 100

  Fly   377 SLDNLKANEFGQSVVVIAATTRPDVLDPGLR-RIGRFDHE-----IAIH----IPSRKERREILR 431
            ::|..|.|:               .:.|..| ||...|.|     .|.|    :|.|..||...|
 Worm   101 AIDESKRNQ---------------KVPPAKRKRIYLSDEEEEDFAEAAHVENTVPERATRRSTRR 150

  Fly   432 IQC--EGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTV 494
            ...  |.|.|..:       |.:|                   .||:.|..:.|  .||:....:
 Worm   151 RSSMHEELGVSEQ-------EESP-------------------VRRTRKAAKRL--GSEQPEENL 187

  Fly   495 TLDDDEPSEDAGETPVP----DSKGEETAKD-------AEAEQKVDGDKETSAKD--KSEGDSPN 546
            ..||..|.|..||..:|    |...|:..:|       .|.|:..:.|:::..||  :.|.||.|
 Worm   188 AADDPLPMEGGGEIVLPIAEIDGMAEQENEDLIEKIGREEEEEGAEEDEQSGEKDPEEEEDDSSN 252

  Fly   547 IETPKKATNGNS-SIKSPQKTPKKSAEKPTD---AAMDVDNVAPE-----EPKKAVEQEVDSSSS 602
            .|:.:::|.... |::..|...:.:|.:..:   |.::...||.:     ....:..:..||.|.
 Worm   253 AESSEESTAPRQYSLRRRQPVVQFNASEARENRRARLEHHRVANQNRHHRNRNGSRRRRSDSDSD 317

  Fly   603 NDEYYEP------TLAELTNFLDNPPEEFADPNFCLTLIDFVDAIKVMQPSAKR----EGFITVP 657
            :|:...|      :...:.|..:.....|...|  :|..:...|..::....::    :|...:.
 Worm   318 SDDMVLPRPDKRQSRPHMHNRGERERGRFMPIN--MTEKELQSAQHILMDRMRKTDAGQGASDID 380

  Fly   658 DTT------WDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAI 716
            ..:      :|.:|.|....:.||..||.|:.|||:.|:..:..|.||:..||||.||||:|:|:
 Worm   381 PMSVDSSVGFDQVGGLGHHIQSLKEVVLFPMLYPEVFEKFRINPPKGVVFYGPPGTGKTLVARAL 445

  Fly   717 ANEA--GIN---FISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGD 776
            |||.  |.|   |...||.:.::.:||||||.:|..|.:|....|.:|||||.|.|.|.||...|
 Worm   446 ANECRRGANKVAFFMRKGADCLSKWVGESERQLRLLFDQAYAMRPSIIFFDEIDGLAPVRSSKQD 510

  Fly   777 GNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEIL 841
            ..::.  ||:.||..|||::.|..|.::.||||.|.:|||:.||||.|..|....|:.:.|.:||
 Worm   511 QIHAS--IVSTLLALMDGLDGRGEVVVIGATNRLDTLDPALRRPGRFDRELRFSLPDLNARRQIL 573

  Fly   842 KATTKNGK--RPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQS-----LNNGDTNLD- 898
            ...|...:  :|:   ...||.||.:|.||.||||..|..:|.:..||..     :.:....||
 Worm   574 DIHTSKWEENKPI---PETLDAIAERTSGYCGADLKFLCTEAVLIGLRSRYPHIYMCSERLKLDV 635

  Fly   899 -DLCVRSQHFQEALQQLRPS 917
             .:.:.|:||..|::::.|:
 Worm   636 ATIKITSEHFGHAMRRITPA 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	183/670 (27%)
		AAA	287..418	CDD:278434	22/111 (20%)
		P-loop_NTPase	679..>716	CDD:304359	18/36 (50%)
		AAA	699..830	CDD:278434	63/135 (47%)
lex-1	NP_502289.2	AAA	424..565	CDD:214640	65/142 (46%)
		AAA	428..563	CDD:278434	63/136 (46%)
		Bromo_AAA	916..1027	CDD:99957

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910