DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and mspn-1

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_501860.1	Gene:	mspn-1 / 177896	WormBaseID:	WBGene00010557	Length:	342	Species:	Caenorhabditis elegans

Alignment Length:	254	Identity:	85/254 - (33%)
Similarity:	134/254 - (52%)	Gaps:	8/254 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   661 WDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFI 725
            ||:||..|::..|||..::.|:::........|:.|.|:||.|||||||||||||:|..||..||
Worm    82 WDEIGGCEELVAELKDRIILPLRFASQSGSHLLSPPRGILLYGPPGCGKTLLAKAVARAAGCRFI 146

  Fly   726 SVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGDGNNSGTRIVNQLLT 790
            :::...|.:.:.|||::...|.|..|:...|.:||.||.||....|.  ...:.|...:..|.:|
Worm   147 NLQVSNLTDKWYGESQKLAAAVFSVAQKFQPTIIFIDEIDSFLRDRQ--SHDHESTAMMKAQFMT 209

  Fly   791 EMDGVEER-KGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLA 854
            ..||.... ..:.::.|||||..:|.||||  |:.....|..|...:|::||....:|.|   :.
Worm   210 LWDGFSSSGDQIIVMGATNRPRDVDAAILR--RMTARFQVPVPNAKQRSQILNVILRNEK---IN 269

  Fly   855 DDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQ 913
            :.|:|.|||...||.:|:||..:.:.|.:...:.::.:|.:....|.:....|:.|:.:
Worm   270 NTVNLGEIAQAAEGLSGSDLKEVCRLALLARAKATVASGGSVNQLLPLEQSDFESAVHK 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	85/254 (33%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	18/36 (50%)
		AAA	699..830	CDD:278434	51/131 (39%)
mspn-1	NP_501860.1	AAA	116..244	CDD:214640	53/131 (40%)
mspn-1	NP_501860.1	AAA	120..249	CDD:278434	52/132 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910