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Protein Alignment smid and cdc-48.2

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_495705.1	Gene:	cdc-48.2 / 174309	WormBaseID:	WBGene00008053	Length:	810	Species:	Caenorhabditis elegans

Alignment Length:	713	Identity:	248/713 - (34%)
Similarity:	363/713 - (50%)	Gaps:	165/713 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 KRDLEVQHPTE-SFRDIGGMDSTLKELCEML-IHIKSPEFYFQLGLLPSRGLLLHGPPGCGKTFL 300
            ||:.|.:...| .:.|:||:...|.::.||: :.::.|:.:..:|:.|.||:||.||||.|||.:
Worm   195 KREEEEEALNEVGYDDLGGVRKQLAQIKEMVELPLRHPQLFKAIGVKPPRGILLFGPPGTGKTLI 259

  Fly   301 ARAISGQLKMPLMEIPATELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKD 365
            |||::.:.......|...|::..:|||||..:|:.|.:....||.:|||||||||...|:.|..:
Worm   260 ARAVANETGAFFFLINGPEIMSKMSGESESNLRKAFAECEKNSPAILFIDEIDAIAPKREKAHGE 324

  Fly   366 MERRIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREIL 430
            :|:||||||::.:|.||..   ..|||||||.||:.:|..|||.||||.||.|.||....|.|||
Worm   325 VEKRIVSQLLTLMDGLKTR---AHVVVIAATNRPNSIDGALRRFGRFDREIDIGIPDAVGRLEIL 386

  Fly   431 RIQCEGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVT 495
            ||..:.:.:...::.:::|....|:|||||.:|.|.||        :::.||       .|..:.
Worm   387 RIHTKNMKLGEDVDLEQVANECHGFVGADLASLCSEAA--------IQQIRE-------KMELID 436

  Fly   496 LDDDEPSEDAGETPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSI 560
            |:||
Worm   437 LEDD------------------------------------------------------------- 440

  Fly   561 KSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEF 625
                                               .:|             ||:.|.|
Worm   441 -----------------------------------TID-------------AEVLNSL------- 450

  Fly   626 ADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLER 690
                 .:|:.:|..|:....|||.||..:..|:|||.|||.|:.::.||:..|..||::||...:
Worm   451 -----AVTMENFRFAMGKSSPSALREAVVETPNTTWSDIGGLQNVKRELQELVQYPVEHPEKYLK 510

  Fly   691 LGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSA 755
            .|:....|||..|||||||||||||||||...||||:|||||:.|:.||||..||..|.:||.:|
Worm   511 FGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDVFDKARAAA 575

  Fly   756 PCVIFFDEFDSLCPKRSDG-GDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILR 819
            |||:||||.||:...|... ||...:..|::||:||||||:..:|.|:|:.|||||||||||:||
Worm   576 PCVLFFDELDSIAKARGGSVGDAGGAADRVINQVLTEMDGMNAKKNVFIIGATNRPDIIDPAVLR 640

  Fly   820 PGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMF 884
            |||||.::|:..|:::.|.:|.||:.:  |.| |:.|:||:.:|..|.|::||||..:.::|...
Worm   641 PGRLDQLIYIPLPDEASRLQIFKASLR--KTP-LSADLDLNFLAKNTVGFSGADLTEICQRACKL 702

  Fly   885 SLRQSLN--------------NGDTNLDDLC------VRSQHFQEALQQLRPSVNEQDRKIYD 927
            ::|:|:.              .|:..::|..      :...||:||::..|.||.:.|.:.|:
Worm   703 AIRESIEREIRQEKERQDRSARGEELMEDELADPVPEITRAHFEEAMKFARRSVTDNDIRKYE 765

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.