Protein Alignment smid and cdc-48.3

DIOPT Version :9

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_492211.1
• Gene: cdc-48.3 / 172586
• WormBaseID: WBGene00010562
• Length: 724
• Species: Caenorhabditis elegans
• Alignment Length: 769
• Identity: 200/769 - (26%)
• Similarity: 312/769 - (40%)
• Gaps: 258/769 - (33%)

  Fly   182 IHVSSSEAIQKLHQVVGNRAKNLSEDAVPRSKDHRNVPGLYQQL----HQNQSRDRLRKFKRDLE 242
            :.|:..|.|:.....:|     :.:|....||......|...|:    .:..:.|.|:....||.
 Worm   187 VTVTPEEPIESKMSAMG-----IDDDKKRNSKVVSTAVGYKIQILNASAEGSTSDVLQTLPTDLS 246

  Fly   243 VQHPTESFRDIGGMDSTLKELCEMLIHIKSPEFYFQLGLLPSR------GLLLHGPPGCGKTFLA 301
                     :|||. .|.|::.|..:            :.|.|      .:|:.|.||.|||.|.
 Worm   247 ---------NIGGC-FTAKQVLEDYV------------ISPVRQKESPCSVLIWGLPGSGKTLLL 289

  Fly   302 RAISGQLKMPLMEIPATELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKDM 366
            :.::      |:...:|..||     |.|.:.|:.....|.   ::.:|
 Worm   290 KEVA------LVLSGSTTYIG-----SCEELMELNGVTTGN---IVIVD---------------- 324

  Fly   367 ERRIVSQLISSLDNLKANEF------GQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKE 425
                |::|  ..:|.|||..      .:...||......:.||.|.|  .||..|..|.:|::.|
 Worm   325 ----VNEL--EKENTKANRALSFLLGDEKKCVILCVRSSETLDIGFR--VRFPIEAEITVPTQDE 381

  Fly   426 RREILRIQCEGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKN 490
            |.:||.......:...:|:.| :|..|.|:.|.||.:|: :||..|..|..:::..
 Worm   382 RLDILSKIGNIYNFPLELHLD-VARHTHGFTGGDLCSLL-KAAKFARGRTHLERVN--------- 435

  Fly   491 MTTVTLDDDEPSEDAGETPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATN 555
                                                                             
 Worm   436 ----------------------------------------------------------------- 435

  Fly   556 GNSSIKSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDN 620
                                                                             
 Worm   436 ----------------------------------------------------------------- 435

  Fly   621 PPEEFADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYP 685
                              ||.|.::|:..|:..:.||:.:|:|||..|:::.|::.||:.|.|:|
 Worm   436 ------------------DARKRIRPTGIRQFILEVPNVSWNDIGGNEELKLEIQQAVIWPQKHP 482

  Fly   686 EMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQR 750
            |..||.|:..|:|:||.|||||.|||:|:|:|:||.:||::||||||.:.:||:||:|:|..|.|
 Worm   483 EAFERFGIDPPAGILLYGPPGCSKTLIARALASEAKMNFLAVKGPELFSKWVGDSEKAIRDLFSR 547

  Fly   751 ARNSAPCVIFFDEFDSLCPKRSDGGDGNNSGT--RIVNQLLTEMDGVEERKGVYILAATNRPDII 813
            ||..||.::||||.|::...|   |...:||.  |::.|||||:||:|:...|.:||||||||.:
 Worm   548 ARQVAPTIVFFDEIDAVGSSR---GSEKSSGVSDRVLAQLLTELDGLEKSSRVILLAATNRPDQL 609

  Fly   814 DPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDV--DLDEIAAQTEGYTGADLAG 876
            |.|:|||||||..:|||.|.:..|..||:..||..|    .||.  .:|::..:|.||:||:|..
 Worm   610 DSALLRPGRLDRAIYVGLPCEVTRRAILEMRTKKMK----FDDTVRTIDKLVEKTSGYSGAELVA 670

  Fly   877 LVKQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQLRPSVNEQDRKIYDKLR 930
            :.:.|:||::|:|       :|...|:..||::||..:.........:|||..:
 Worm   671 VCRTAAMFAMRES-------IDATIVQWTHFEQALAAVVSRTEAYLLEIYDDFK 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	178/663 (27%)
		AAA	287..418	CDD:278434	32/136 (24%)
		P-loop_NTPase	679..>716	CDD:304359	20/36 (56%)
		AAA	699..830	CDD:278434	72/132 (55%)
cdc-48.3	NP_492211.1	TIP49	<247..720	CDD:332389	187/695 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D169540at33208
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820