DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AgaP_AGAP001407

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_321726.5	Gene:	AgaP_AGAP001407 / 1281769	VectorBaseID:	AGAP001407	Length:	392	Species:	Anopheles gambiae

Alignment Length:	462	Identity:	128/462 - (27%)
Similarity:	202/462 - (43%)	Gaps:	119/462 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   510 VPDSKGEETAKD--------AEAEQKVDGDKETSAK-----DKSEGDSPNIETP----------- 550
            |.|:..|:..:|        .|.|.::...:||..:     ||||.|...:::.
Mosquito     3 VADASREKALEDYRKKLLEHKEVESRLKEVRETLKELTKQFDKSENDLKALQSVGQIVGEVLKQL 67

  Fly   551 ------KKATNGNSSI----KSPQKTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDE 605
                  .|||||...:    :...||..||.   |..|:|:..:.   ..:.:.:|||....|..
Mosquito    68 TEDKFIVKATNGPRYVVGCRRQLDKTKLKSG---TRVALDMTTLT---IMRYLPREVDPLVYNMS 126

  Fly   606 YYEPTLAELTNFLDNPPEEFADPNFCLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKI 670
            :.:|                                               .:.|:..||.|.:.
Mosquito   127 HEDP-----------------------------------------------GEVTYSAIGGLSEQ 144

  Fly   671 REELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNM 735
            ..||:..:..|:..||:..|:|:|.|.|.||.||||.||||||:|:|::...||:.|....:::.
Mosquito   145 IRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDK 209

  Fly   736 YVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKR-SDGGDGNNSGTRIVNQLLTEMDGVEERK 799
            |:|||.|.:|..|..||:..||:||.||.|::..:| |:|...:....|.:.:||.:|||.:...
Mosquito   210 YIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLG 274

  Fly   800 GVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILK----ATTKNGKRPVLADDVDLD 860
            .|.::.||||||.:|||:|||||||..:.:..|.:..|.||||    ...|:|       |:|.:
Mosquito   275 QVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHAAPIAKHG-------DIDYE 332

  Fly   861 EIAAQTEGYTGADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQLRPSVNEQDRKI 925
            .:...::.:.||||..:..:|.:|::|....         .|..:.|.:|:           ||:
Mosquito   333 AVVKLSDNFNGADLRNVCTEAGLFAIRAERE---------YVIQEDFMKAV-----------RKV 377

  Fly   926 YDKLRLK 932
            .|..||:
Mosquito   378 ADNKRLE 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	123/447 (28%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	20/36 (56%)
		AAA	699..830	CDD:278434	59/131 (45%)
AgaP_AGAP001407	XP_321726.5	RPT1	6..390	CDD:224143	126/459 (27%)
AgaP_AGAP001407	XP_321726.5	AAA	174..306	CDD:278434	59/131 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910