DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AgaP_AGAP001522

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_321602.5	Gene:	AgaP_AGAP001522 / 1281656	VectorBaseID:	AGAP001522	Length:	445	Species:	Anopheles gambiae

Alignment Length:	279	Identity:	70/279 - (25%)
Similarity:	113/279 - (40%)	Gaps:	58/279 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   661 WDDIGALEKIREE-LKLAVLAPVKYPEMLERLG-----LTAPSGVLLCGPPGCGKTLLAKAIANE 719
            |:.:     |.|| :|.:|||..:...:..|.|     :|.....|..||||.|||.|.||||.:
Mosquito   114 WESL-----IYEEGIKDSVLAFAETSMLFARKGVDKNLITCNRLALFHGPPGTGKTSLCKAIAQK 173

  Fly   720 AGI---------NFISVKGPELMNMYVGESERAVRACFQRA------RNSAPCVIFFDEFDSLCP 769
            ..|         :.:.:....|.:.:..||.:.|:..|...      ..|..||: .||.:|:..
Mosquito   174 LSIRLNEQYRHAHLVEINSHSLFSRWFSESGKLVQKVFSEIVALLEDERSLVCVL-VDEIESIAY 237

  Fly   770 KRSDGGDGNNSGT-RIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPE 833
            .|........|.: |:||.:||::|.:.....|:|||.:|..|.||.|.|  .|.|.:.|:..|.
Mosquito   238 ARDRISSNEPSDSIRVVNAVLTQLDRLRRFPNVFILATSNLTDSIDAAFL--DRADFVQYIDHPT 300

  Fly   834 QSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSLNNGDTNLD 898
            :....:|.::...|                .||        .|:|::.:..|.|:.........|
Mosquito   301 EPAIYDIYRSALYN----------------LQT--------IGIVEKEANTSNRRLSQTAANTTD 341

  Fly   899 DLCVRSQHFQEALQQLRPS 917
            .:    ..:::|:...:||
Mosquito   342 GI----PSYEQAIDPAKPS 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	70/279 (25%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	15/41 (37%)
		AAA	699..830	CDD:278434	46/146 (32%)
AgaP_AGAP001522	XP_321602.5	AAA	154..300	CDD:214640	46/148 (31%)
AgaP_AGAP001522	XP_321602.5	AAA	154..297	CDD:278434	46/145 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810