DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment smid and AgaP_AGAP004266

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_313188.3	Gene:	AgaP_AGAP004266 / 1274111	VectorBaseID:	AGAP004266	Length:	424	Species:	Anopheles gambiae

Alignment Length:	287	Identity:	71/287 - (24%)
Similarity:	123/287 - (42%)	Gaps:	63/287 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 HPTESFRDIGG--MDSTLKE--LCEMLIHIKSPEFYFQLGLLPSRGLLLHGPPGCGKTFLARAIS 305
            ||.:. |.||.  :|..:.|  |.:....||:|::|...|:...||.||||||||||:....|::
Mosquito   182 HPRKR-RPIGSVVLDEGVSERILRDCREFIKNPQWYSDRGIPYRRGYLLHGPPGCGKSSFITALA 245

  Fly   306 GQLKMPLMEIPATELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQ------WASK 364
            |:::..:..:..:|     .|.:::|:..:.:.|...|  ::.:::|||...:||      .|.:
Mosquito   246 GEIEFGICLLNLSE-----RGLTDDRLNHLMNVAPQQS--IILLEDIDAAFVSRQDTLQQKAAYE 303

  Fly   365 DMERRIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREI 429
            .:.|...|.|::.||.:.:.|   :.:|...|...:.|||.|.|.||.|.:..:...||.:..::
Mosquito   304 GLNRVTFSGLLNCLDGVASTE---ARIVFMTTNYLERLDPALIRPGRVDVKEYVGHCSRHQLEQM 365

  Fly   430 LRIQCEGLSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTV 494
            .|                     ..|.|.|..|             :.:.|.|..||..:|::
Mosquito   366 FR---------------------RFYTGTDAEA-------------NARIFAERVAADGRNVS-- 394

  Fly   495 TLDDDEPSEDAGETPVPDSKGEETAKD 521
                  |::..|...|.....::|..|
Mosquito   395 ------PAQVQGYFMVHKMSDQQTVLD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	62/257 (24%)
		AAA	287..418	CDD:278434	39/136 (29%)
		P-loop_NTPase	679..>716	CDD:304359
		AAA	699..830	CDD:278434
AgaP_AGAP004266	XP_313188.3	BCS1_N	23..192	CDD:214980	5/10 (50%)
		AAA	224..355	CDD:214640	41/140 (29%)
		AAA	227..355	CDD:278434	39/137 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910