DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AgaP_AGAP003215

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_312923.4	Gene:	AgaP_AGAP003215 / 1273890	VectorBaseID:	AGAP003215	Length:	438	Species:	Anopheles gambiae

Alignment Length:	416	Identity:	124/416 - (29%)
Similarity:	203/416 - (48%)	Gaps:	76/416 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   530 GDKETSAKDKSEGDSPNIET-----PKKATNGNSSIKSPQKTPKK-------SAEKPTD-AAMDV 581
            |||:.. |||.:...|.|.|     .:||...::::|.||.||..       ..|:..| ..|:.
Mosquito    11 GDKDKD-KDKKKKYEPPIPTRVGKKKRKAKGPDAALKLPQVTPHTRCRLKLLKLERIKDYLLMEE 74

  Fly   582 DNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPP-----EEFADPNFCL--------- 632
            :.:..:|..|..|::::...|          ::.:...:|.     ||..|.|..:
Mosquito    75 EFIRNQERLKPQEEKIEEERS----------KVDDLRGSPMSVGTLEEIIDDNHAIVSTSVGSEH 129

  Fly   633 --TLIDFVDAIKVMQPSAK-----------------REGFITV------PDTTWDDIGALEKIRE 672
              :::.|||..: ::|...                 .:..:||      |..|:.|||.|:...:
Mosquito   130 YVSILSFVDKDQ-LEPGCSVLLNHKVHAVVGVLGDDTDPMVTVMKLEKAPQETYADIGGLDTQIQ 193

  Fly   673 ELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYV 737
            |:|.:|..|:.:||..|.:|:..|.||:|.||||.||||||||:||:....|:.|.|.||:..|:
Mosquito   194 EIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYL 258

  Fly   738 GESERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGDGNNSG-----TRIVNQLLTEMDGVEE 797
            |:..:.||..|:.|...||.::|.||.|::..||.|    :|||     .|.:.:||.::||.:.
Mosquito   259 GDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYD----SNSGGEREIQRTMLELLNQLDGFDS 319

  Fly   798 RKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEI 862
            |..|.::.||||.:.:|||::||||:|..:....|::..:..|....|   .|..||:||:|.|:
Mosquito   320 RGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFNIHT---ARMTLAEDVNLSEL 381

  Fly   863 AAQTEGYTGADLAGLVKQASMFSLRQ 888
            ....:..:|||:..:..:|.:.:||:
Mosquito   382 IMAKDDLSGADIKAICTEAGLMALRE 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	124/416 (30%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	20/36 (56%)
		AAA	699..830	CDD:278434	58/135 (43%)
AgaP_AGAP003215	XP_312923.4	PTZ00361	1..438	CDD:185575	124/416 (30%)
		Prot_ATP_ID_OB	106..>174	CDD:293059	10/68 (15%)
		AAA	220..353	CDD:278434	58/136 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910