DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AgaP_AGAP000616

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_310465.3	Gene:	AgaP_AGAP000616 / 1271616	VectorBaseID:	AGAP000616	Length:	427	Species:	Anopheles gambiae

Alignment Length:	463	Identity:	125/463 - (26%)
Similarity:	211/463 - (45%)	Gaps:	74/463 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   500 EPSEDAGETPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSIKSPQ 564
            |.||:.||..:..|..|..::....:.::...|....:...|..:.|    :|..:....||..:
Mosquito    12 EDSEELGEEVLRMSTDELVSRTRLMDNEIKIMKSEVVRINHELQTQN----EKIKDNTEKIKVNK 72

  Fly   565 KTPKKSAEKPTDAAMDVDNVAPEEPKKAVEQE--------VDSSSSNDEYYEPTLAELTN----- 616
            ..|...:.  ....:|||....|:....|..:        |..:|:...|:.|.:..:.:
Mosquito    73 TLPYLVSN--VIELLDVDPQEEEDDGAVVVLDSQRKGKCAVIKTSTRQTYFLPVIGLVDSDKLKP 135

  Fly   617 ------------FLDNPPEEFADPNFCLTLIDFVDA-IKVMQPSAKREGFITVPDTTWDDIGALE 668
                        .|:..|.|:             || :|.|:...:       |...:.|||.|:
Mosquito   136 GDLVGVNKDSYLILETLPAEY-------------DARVKAMEVDER-------PTEQYSDIGGLD 180

  Fly   669 KIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELM 733
            |..:||..||:.|:.:.:..:.||:..|.||||.||||.||||||:|.|.:....|:.:.||:|:
Mosquito   181 KQIQELIEAVVLPMTHKDKFKNLGIHPPKGVLLYGPPGTGKTLLARACAAQTKSTFLKLAGPQLV 245

  Fly   734 NMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKRSDGGD-GNNSGTRIVNQLLTEMDGVEE 797
            .|::|:..:.||..|..|:..:|.:||.||.|::..||.|... |:....|.:.:||.::||...
Mosquito   246 QMFIGDGAKLVRDAFALAKEKSPAIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFSS 310

  Fly   798 RKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEI 862
            ...:.::|||||.||:|||:||.||||..:....|.:..|..|::.   :.::..::.||:.:|:
Mosquito   311 TADIKVIAATNRVDILDPALLRSGRLDRKIEFPHPNEEARARIMQI---HSRKMNVSPDVNFEEL 372

  Fly   863 AAQTEGYTGADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQHFQEALQQLRPSVNEQDRKIYD 927
            |..|:.:.||....:..:|.|.:||:|.         :.|..:.|.:|:.::      |.:|
Mosquito   373 ARSTDDFNGAQCKAVCVEAGMIALRRSA---------VSVIHEDFMDAIMEV------QSKK--- 419

  Fly   928 KLRLKYAA 935
            |..|.|.|
Mosquito   420 KANLNYFA 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	119/445 (27%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	18/36 (50%)
		AAA	699..830	CDD:278434	56/131 (43%)
AgaP_AGAP000616	XP_310465.3	RPT1	32..420	CDD:224143	114/434 (26%)
AgaP_AGAP000616	XP_310465.3	AAA	211..343	CDD:278434	56/131 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910