DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AgaP_AGAP011174

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_309476.2	Gene:	AgaP_AGAP011174 / 1270756	VectorBaseID:	AGAP011174	Length:	434	Species:	Anopheles gambiae

Alignment Length:	492	Identity:	141/492 - (28%)
Similarity:	213/492 - (43%)	Gaps:	117/492 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   510 VPDSKGEETAK----------DAEAEQKVD---------GDKETSAKDKSEGDSPNIETPKKATN 555
            :||..|::..|          :.||..:||         |....|.|...|    :|:...|..|
Mosquito     1 MPDHLGDDMRKVKSDNKEVEPEIEALDEVDIELLKTYGQGQYHKSIKQIDE----DIQKAMKQVN 61

  Fly   556 GNSSIKSPQKTPKKSAEKPT--------DAAMDVDNVAPEEPKKAVE-QEVDSSSSNDEYYEPTL 611
            ..:.||          |..|        |.|.|...:..|:|.:... .::.::.|:|..|...:
Mosquito    62 ELTGIK----------ESDTGLAPPALWDLASDKQILQNEQPLQVARCTKIINADSDDPKYIINV 116

  Fly   612 AELTNFLDNPPEEFADPNFCLTLIDFVDAIKVMQPSAKREGF----------------------I 654
            .:...|                ::|..|::   .|:...||.                      :
Mosquito   117 KQFAKF----------------VVDLADSV---APTDIEEGMRVGVDRNKYQIHIPLPPKIDPTV 162

  Fly   655 TV------PDTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCGPPGCGKTLLA 713
            |:      ||.|:.|:|..::..|:|:..|..|:.:||....||:..|.||||.||||.||||.|
Mosquito   163 TMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPEKFVNLGIEPPKGVLLFGPPGTGKTLCA 227

  Fly   714 KAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLCPKR-SDGGDG 777
            :|:||.....||.|.|.||:..||||..|.||..|:.||:...|:|||||.|::...| .||..|
Mosquito   228 RAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARSKKACLIFFDEIDAIGGARFDDGAGG 292

  Fly   778 NNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILK 842
            :|...|.:.:|:.::||.:.|..:.:|.||||||.:|||::||||||..:..|.|:...||.|.|
Mosquito   293 DNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKVEFGLPDLEGRTHIFK 357

  Fly   843 --ATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSLNNGDTNLDDLCVRSQ 905
              |.:.:.:|     |:..:.:|......|||::..:..:|.||::|....         ....:
Mosquito   358 IHARSMSVER-----DIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRK---------VATEK 408

  Fly   906 HFQEALQQLRPSVNEQDRKIYDKLRLKYAAPRVPTLN 942
            .|.||:.::        .|.|.|..   |.||..|.|
Mosquito   409 DFLEAVNKV--------IKSYAKFS---ATPRYMTYN 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	133/467 (28%)
		AAA	287..418	CDD:278434
		P-loop_NTPase	679..>716	CDD:304359	19/36 (53%)
		AAA	699..830	CDD:278434	64/131 (49%)
AgaP_AGAP011174	XP_309476.2	Anticodon_Ia_like	<15..>75	CDD:299868	15/73 (21%)
		RPT1	21..431	CDD:224143	135/467 (29%)
		AAA	213..346	CDD:278434	64/132 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910