DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smid and AgaP_AGAP012537

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	XP_307605.4	Gene:	AgaP_AGAP012537 / 1269024	VectorBaseID:	AGAP012537	Length:	175	Species:	Anopheles gambiae

Alignment Length:	174	Identity:	34/174 - (19%)
Similarity:	75/174 - (43%)	Gaps:	22/174 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 LIGGISGESEERIREVFDQAIGYSPCVLFIDEID------AIGGNRQWASKDMERRIVSQLISSL 378
            ::|...|....:||:.||.|...:...:.:|.|:      .||  .::::..::..:|  |:.
Mosquito     1 MVGFSEGAKCLQIRKYFDDAYRSTFSCILVDNIERLLDYGPIG--PRYSNLTLQALLV--LLK-- 59

  Fly   379 DNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKL 443
               |:...|:.::::..|:|..||: .:..:..|  ...:|:|:......::.:..:...|..:.
Mosquito    60 ---KSPPKGKKLLILCTTSRRQVLE-DMEMLSAF--TAVLHVPNLSTADHLIAVLEQEPDVFGRN 118

  Fly   444 NYDKIAELTPG---YVG-ADLMALVSRAASVAVKRRSMKKFREL 483
            ....|.:...|   :|| ..|:.|:..|..:..:.|.||...:|
Mosquito   119 ELAAIYKRLKGRRIFVGIKKLLDLIDLARQMDPQTRMMKFLSKL 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	34/174 (20%)
		AAA	287..418	CDD:278434	20/103 (19%)
		P-loop_NTPase	679..>716	CDD:304359
		AAA	699..830	CDD:278434
AgaP_AGAP012537	XP_307605.4	AAA	<3..97	CDD:214640	21/105 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900