Protein Alignment SBK1 and mek1

DIOPT Version :9

• Sequence 1: XP_005255372.1
• Gene: SBK1 / 388228
• HGNCID: 17699
• Length: 458
• Species: Homo sapiens
• Sequence 2: NP_594908.1
• Gene: mek1 / 2541604
• PomBaseID: SPAC14C4.03
• Length: 445
• Species: Schizosaccharomyces pombe
• Alignment Length: 429
• Identity: 112/429 - (26%)
• Similarity: 174/429 - (40%)
• Gaps: 93/429 - (21%)

Human     6 DDVPAFCFVCFHREEEEELLEEVPLRREKMSVGCPEPEPPRSLTC-------------------- 50
            |||.|..|| |.....:.:|.  ..:.|.:|||       ||.||
pombe    36 DDVLARLFV-FSSSSPQTVLN--VKKYEDVSVG-------RSNTCNYQLLQFTASYKHFRVYSVL 90

Human    51 ----------CGPGTAPGP-------GAGVPLLTEDMQALTLRTLAA--------SDVTKHYELV 90
                      |...::.|.       |.|..:|..|...|.:|..|:        :|...|:|..
pombe    91 IDDDMDPLVYCEDQSSNGTFLNHRLIGKGNSVLLSDGDILDVRHCASFLFQQKYTTDNDFHHEYA 155

Human    91 RE--------LGKGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFL--REVSITNSLSSSPFII 145
            .|        ||.|.:.::.:.:...||.:.|.|.::|.|...|.|.  .|::|...| ..|.||
pombe   156 GERFNITQRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRKL-DHPNII 219

Human   146 KVFDVVFETEDCYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQLVHRDIK 210
            || ::.:.:|..:...:|....||||..:.....:||.|....:.|:...|.::|.:.::|||:|
pombe   220 KV-NMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHRDLK 283

Human   211 PENVLLFDRE--CRRVKLADFGMTR--RVGCRVKRVSGTIPYTAPEV------CQAGRADGLAVD 265
            .||:|:....  ..|:.|.|||:.|  :.|.|:....||..|||||:      .|..:.:.....
pombe   284 LENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGRSQVEKENSSGYG 348

Human   266 TGVDVWAFGVLIFCVLTGNFPWEAASGADAFFEEFVRWQRGRLPGLPSQWRRFTEPALRMFQRLL 330
            ..||:|:.||::|.:|:||.|    |.||...|:.|.::       ...|:..:..|..:...||
pombe   349 KEVDLWSLGVIMFLLLSGNSP----SFADGVKEKQVDFR-------DPVWKSVSRQAKDLISNLL 402

Human   331 ALEPERRGPAKEVFR---FLKHELTSELRRRPSHRARKP 366
            ...|..|...|:...   |.:|  :|.|.:....|..||
pombe   403 KTNPPDRFTVKQCLSHPWFARH--SSRLTKLYETRILKP 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SBK1	XP_005255372.1	S_TKc	87..350	CDD:214567	79/285 (28%)
		STKc_SBK1	93..351	CDD:270889	78/272 (29%)
mek1	NP_594908.1	FHA	39..141	CDD:238017	22/111 (20%)
		STKc_CAMK	163..420	CDD:270687	76/269 (28%)
		S_TKc	164..421	CDD:214567	76/269 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910