DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SBK1 and sbk1

DIOPT Version :9

Sequence 1:	XP_005255372.1	Gene:	SBK1 / 388228	HGNCID:	17699	Length:	458	Species:	Homo sapiens
Sequence 2:	XP_031748321.1	Gene:	sbk1 / 100125030	XenbaseID:	XB-GENE-5816218	Length:	415	Species:	Xenopus tropicalis

Alignment Length:	449	Identity:	303/449 - (67%)
Similarity:	352/449 - (78%)	Gaps:	36/449 - (8%)

- Green bases have known domain annotations that are detailed below.

Human    10 AFCFVCFHREEEEELLEEVPLRREKMSVGCPEPEPPRSLTCCGPGTAPGPGAGVPLLTEDMQALT 74
            :|||:||||    :.:.::|.....||.|..|.||.|.|.||          |||::|||||||.
Frog     3 SFCFICFHR----KAMRQMPGTSVNMSAGSVEQEPARKLGCC----------GVPVITEDMQALA 53

Human    75 LRTLAASDVTKHYELVRELGKGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLS 139
            :|:|:.|:|.|||||:|:|||||||:|:||.:|.||.|||||||||:|||||:||||.|:|::||
Frog    54 IRSLSGSEVQKHYELIRDLGKGTYGRVELVSHKSTGNKMALKFVNKNKTKLKSFLREFSVTSALS 118

Human   140 SSPFIIKVFDVVFETEDCYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQL 204
            .|||||:.|.|:|:||:|||||||||||||||||||||||||||.||||||||||||||||.:.|
Frog   119 CSPFIIRAFHVLFQTEECYVFAQEYAPAGDLFDIIPPQVGLPEDMVKRCVQQLGLALDFMHSKSL 183

Human   205 VHRDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGRADGLAVDTGVD 269
            |||||||||||||||||||||||||||||:||||||||||||||||||||||||.:|..|:|.:|
Frog   184 VHRDIKPENVLLFDRECRRVKLADFGMTRKVGCRVKRVSGTIPYTAPEVCQAGRTEGFPVETSLD 248

Human   270 VWAFGVLIFCVLTGNFPWEAASGADAFFEEFVRWQRGRLPGLPSQWRRFTEPALRMFQRLLALEP 334
            |||||||||||||||||||:||..||||||||.||:|||||||||||||::.|||||:||||||.
Frog   249 VWAFGVLIFCVLTGNFPWESASPGDAFFEEFVHWQKGRLPGLPSQWRRFSDNALRMFKRLLALEA 313

Human   335 ERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRPPAAGPLRLEAPGPLKRTVLTESGSGSRP 399
            |:|.|.||||.::|:||.||:|||||:|:||..||:.|:. |.|.|.|.|||||:|||.||..|
Frog   314 EKRSPVKEVFFYIKYELLSEVRRRPSYRSRKQTGDKLPSV-PQRHENPTPLKRTILTEGGSSPR- 376

Human   400 APPAVGSVPLPVPVPVPVPVPVPVPEPGLAPQGPPGRTDGRADKSKGQVVLATAIEICV 458
                               .|..:|||| .|....||||||.||||.|::|||||||||
Frog   377 -------------------APHSLPEPG-QPSAGSGRTDGRQDKSKAQMLLATAIEICV 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SBK1	XP_005255372.1	S_TKc	87..350	CDD:214567	213/262 (81%)
SBK1	XP_005255372.1	STKc_SBK1	93..351	CDD:270889	209/257 (81%)
sbk1	XP_031748321.1	STKc_SBK1	72..330	CDD:270889	209/257 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	447	1.000	Domainoid score	I4804
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H17084
Inparanoid	1	1.050	588	1.000	Inparanoid score	I6606
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221624at2759
OrthoFinder	1	1.000	-	-		FOG0002130
OrthoInspector	1	1.000	-	-		oto156110
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X768
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.060