DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment akirin and akirin1

DIOPT Version :9

Sequence 1:	NP_001189058.1	Gene:	akirin / 38821	FlyBaseID:	FBgn0082598	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001016080.1	Gene:	akirin1 / 548834	XenbaseID:	XB-GENE-5820002	Length:	186	Species:	Xenopus tropicalis

Alignment Length:	206	Identity:	76/206 - (36%)
Similarity:	119/206 - (57%)	Gaps:	25/206 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAC-ATLKRALDWES-MNQRPPKRRRCNPFGQAGSNAGPASPSRDG--PSTSAGLPHTPSNRFAK 61
            ||| |||||::::|: |:.:.||||||.|.  .||.|.| ||.|.|  |....| ...|..:...
Frog     1 MACGATLKRSMEFEALMSPQSPKRRRCAPL--PGSPATP-SPQRCGIRPEMQQG-QQQPLLQLGG 61

  Fly    62 DSTEPSPFSESSLAKMSPDKMAESLCNEIKRLHKRKQLPITSSALERMQDSESSGSEMGPESPRR 126
            |            .:::|:::.:::..|..|..:|:||   ..|..:.:...|:..:....|...
Frog    62 D------------RRLTPEQILQNIKQEYTRYQRRRQL---EGAFNQSEAGVSNEVQASCSSLTA 111

  Fly   127 PDSPQNLMRHGEKALFTFKQVQLICESMIKERENQLRERYESVLTTKLAEQYDAFVKFTYDQIQR 191
            |.||.:|::. ::..|:.:||.::||.::|:.|:::||.||.:|..||||||::|||||:|||.|
Frog   112 PSSPGSLVKK-DQPTFSLRQVGILCERLLKDHEDKIREEYEQILNIKLAEQYESFVKFTHDQIMR 175

  Fly   192 RYEAAP-SYLS 201
            ||.|.| ||:|
Frog   176 RYGARPASYVS 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
akirin	NP_001189058.1	akirin	2..201	CDD:425410	74/203 (36%)
akirin1	NP_001016080.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64		29/78 (37%)
akirin1	NP_001016080.1	Nuclear localization signal	22..27		4/4 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	122	1.000	Domainoid score	I5587
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	122	1.000	Inparanoid score	I4593
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1420469at2759
OrthoFinder	1	1.000	-	-		FOG0003080
OrthoInspector	1	1.000	-	-		otm49110
Panther	1	1.100	-	-	O	PTHR13293
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4225
SonicParanoid	1	1.000	-	-		X2925
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100