DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment akirin and Akirin2

DIOPT Version :9

Sequence 1:	NP_001189058.1	Gene:	akirin / 38821	FlyBaseID:	FBgn0082598	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001007590.2	Gene:	Akirin2 / 433693	MGIID:	1889364	Length:	201	Species:	Mus musculus

Alignment Length:	210	Identity:	83/210 - (39%)
Similarity:	125/210 - (59%)	Gaps:	18/210 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAC-ATLKRALDWES-MNQRPPKRRRCNPFGQAGSNAGPASPSRDGPSTSAGLPHTPSNRFAKDS 63
            ||| |||||.||::. ::...||||||.|.....|.|  |||:....:.:|........::.:
Mouse     1 MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPASAA--ASPAAATAAAAASAAAASPQKYLR-- 61

  Fly    64 TEPSPFSESSLAKMSPDKMAESLCNEIKRLHKRKQLPITSSALERMQDSESSGSE------MGPE 122
            .|||||.:.| ::::.:::..::..|.||:.||:.|   .::.::.....:|.|:      .||.
Mouse    62 MEPSPFGDVS-SRLTTEQILYNIKQEYKRMQKRRHL---EASFQQADPGCTSDSQPHAFLISGPA 122

  Fly   123 SPRRPDSPQNLMRHGEKALFTFKQVQLICESMIKERENQLRERYESVLTTKLAEQYDAFVKFTYD 187
            ||....:..:.::. |:.|||.:||.:|||.::||||.::||.||.:|.||||||||||||||:|
Mouse   123 SPGTSSATSSPLKK-EQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHD 186

  Fly   188 QIQRRYEAAP-SYLS 201
            ||.|||...| ||:|
Mouse   187 QIMRRYGEQPASYVS 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
akirin	NP_001189058.1	akirin	2..201	CDD:425410	81/207 (39%)
Akirin2	NP_001007590.2	Nuclear localization signal	23..28		4/4 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836029
Domainoid	1	1.000	130	1.000	Domainoid score	I5189
eggNOG	1	0.900	-	-		E1_KOG4330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9988
Inparanoid	1	1.050	130	1.000	Inparanoid score	I4620
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48613
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003080
OrthoInspector	1	1.000	-	-		otm43937
orthoMCL	1	0.900	-	-		OOG6_105453
Panther	1	1.100	-	-	LDO	PTHR13293
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4225
SonicParanoid	1	1.000	-	-		X2925
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790