DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sh3beta and Sh3bgr

DIOPT Version :9

Sequence 1:	NP_001189057.1	Gene:	Sh3beta / 38820	FlyBaseID:	FBgn0035772	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_006248246.1	Gene:	Sh3bgr / 498066	RGDID:	1563599	Length:	204	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	80/247 - (32%)
Similarity:	126/247 - (51%)	Gaps:	50/247 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLKVYVSGMSGNKEVKKRQQRVLMILDSKNIKYDTVDITEPGKESEKELMQ-----NKSTSNGG 60
            ||:||:|:..||:..::|:||.|:..|::..|.:..:||.  |.|..::.|:     .|...||
  Rat     1 MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIA--GDEDNRKWMRENVPGEKKPQNG- 62

  Fly    61 TVSDPEPRHPLPPQLFNDDEYCGDYDAFDMANEIDTLEVFLKLAPADTTAVSTAQIELKQENGDA 125
                    .|||||:||:::||||:|:|..|.|.:.:..||.|||...:.|:
  Rat    63 --------IPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVT------------- 106

  Fly   126 KKEEAETEAEDKKTEAGDGDVDVKEEAAEKAENEDGKDKENSKGEDEDADEENAEQKTETEESGD 190
            |.|||        :...:|||..:.|.|     .:|.:|....||.| |.:|::|...|..:|.:
  Rat   107 KSEEA--------SSLPNGDVAGEAEGA-----AEGTEKAEESGETE-AQKEDSEDTGELSQSQE 157

  Fly   191 KKTEEKTTDAEGETQEKSEEVDTKEKSEVESTKDDEVGKSEDVKDDEDEKSE 242
            ||.|      |||..||.||.:|.|::| |:|:....|::|:..::|..:.|
  Rat   158 KKEE------EGEEGEKGEEGETAEETE-EATEGGAEGEAEEEPEEEGGEEE 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sh3beta	NP_001189057.1	Thioredoxin_like	1..104	CDD:294274	38/107 (36%)
Sh3bgr	XP_006248246.1	SH3BGR	1..98	CDD:252868	38/107 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9088
eggNOG	1	0.900	-	-		E1_KOG4023
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I5030
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1508713at2759
OrthoFinder	1	1.000	-	-		FOG0000625
OrthoInspector	1	1.000	-	-		otm46113
orthoMCL	1	0.900	-	-		OOG6_110742
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4396
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.770