Protein Alignment CTCF and Zfp966

DIOPT Version :10

• Sequence 1: NP_648109.1
• Gene: CTCF / 38817
• FlyBaseID: FBgn0035769
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001170878.1
• Gene: Zfp966 / 667962
• MGIID: 3709288
• Length: 485
• Species: Mus musculus
• Alignment Length: 332
• Identity: 116/332 - (34%)
• Similarity: 164/332 - (49%)
• Gaps: 16/332 - (4%)

  Fly   281 SSTSQ--NSNASGHK-YSCPHCPYTASKKFLITRHSRSHDVEPSFKCSICERSFRSNVGLQNHIN 342
            |||.|  ....:|.| |.|.||....:|...:..|.|.|..|..::|..|.::|..:..|..|..
Mouse   162 SSTLQIHKRKHTGEKPYECNHCVKAFAKMSKLQIHKRIHTGEKPYECKQCGKAFTQSSHLGIHKR 226

  Fly   343 THMGNKPHKCKLCESAFTTSGELVRHTRYKHTKEKPHKCTECTYASVELTKLRRHMTCHTGERPY 407
            ||.|.||::||.|..|||.|..|..| :..||.|||::|.:|..|.|...:|:.|...||||:||
Mouse   227 THTGEKPYECKQCGKAFTRSSTLQTH-KQTHTGEKPYECKQCDKAFVRRGELQIHKRTHTGEKPY 290

  Fly   408 QCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPT 472
            :|..|..|......|:.|...|||||.|:|..|...|..|::|:.||..|: .:|| ::|..|..
Mouse   291 ECKQCGKAFAQSGTLQIHKRTHTGEKPYECKQCGKAFAHSSTLQIHKRTHT-GEKP-YECKQCDK 353

  Fly   473 TCGRKADLRVHIKHMHTSDVPMTCRRCGQQLPDRYQYKLHVKSHEGEKCYSCKLCSYASVTQRHL 537
            ...::.:|::| |..||.:.|..|::||:........::|.::|.|||.:.|..|..|.|....|
Mouse   354 AFVKRGELQIH-KQTHTGEKPYECKQCGKAFAQSGTLQVHERTHTGEKPFECNQCGKAFVQCIAL 417

  Fly   538 ASHMLIHLDEKPFHCDQCPQAFRQRQLLRRHMNLVHNEEYQPPEPREKLHKCPSCPREFTHKGNL 602
            ..|...|..|||:.|.||.:||.....|:.|.. .|.        .||.::|..|.:.|.|...|
Mouse   418 RIHERTHTGEKPYECKQCGKAFAHSNTLQIHKR-THT--------GEKPYECKQCGKAFAHSSTL 473

  Fly   603 MRHMETH 609
            ..|.:||
Mouse   474 QIHKQTH 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTCF	NP_648109.1	FAP	116..>202	CDD:429334
		C2H2 Zn finger	296..316	CDD:275368	6/19 (32%)
		COG5048	321..>621	CDD:227381	101/289 (35%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..373	CDD:275368	9/20 (45%)
		C2H2 Zn finger	381..401	CDD:275368	6/19 (32%)
		zf-H2C2_2	394..415	CDD:463886	10/20 (50%)
		C2H2 Zn finger	409..429	CDD:275368	5/19 (26%)
		zf-H2C2_2	422..446	CDD:463886	11/23 (48%)
		C2H2 Zn finger	437..457	CDD:275368	7/19 (37%)
		C2H2 Zn finger	467..485	CDD:275368	4/17 (24%)
		C2H2 Zn finger	496..516	CDD:275370	4/19 (21%)
		C2H2 Zn finger	524..544	CDD:275368	6/19 (32%)
		zf-H2C2_2	536..561	CDD:463886	11/24 (46%)
		C2H2 Zn finger	552..573	CDD:275368	7/20 (35%)
		zf-C2H2	587..609	CDD:395048	6/21 (29%)
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
Zfp966	NP_001170878.1	KRAB	22..63	CDD:460171
		COG5048	94..478	CDD:227381	114/328 (35%)
		C2H2 Zn finger	99..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368	4/9 (44%)
		C2H2 Zn finger	180..200	CDD:275368	6/19 (32%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		C2H2 Zn finger	236..256	CDD:275368	9/20 (45%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		C2H2 Zn finger	292..312	CDD:275368	5/19 (26%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		C2H2 Zn finger	348..368	CDD:275368	5/20 (25%)
		C2H2 Zn finger	376..396	CDD:275368	4/19 (21%)
		C2H2 Zn finger	404..424	CDD:275368	6/19 (32%)
		C2H2 Zn finger	432..452	CDD:275368	7/20 (35%)
		C2H2 Zn finger	460..480	CDD:275368	6/19 (32%)