Protein Alignment CTCF and gl

DIOPT Version :10

• Sequence 1: NP_648109.1
• Gene: CTCF / 38817
• FlyBaseID: FBgn0035769
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001262708.1
• Gene: gl / 42210
• FlyBaseID: FBgn0004618
• Length: 679
• Species: Drosophila melanogaster
• Alignment Length: 456
• Identity: 109/456 - (23%)
• Similarity: 167/456 - (36%)
• Gaps: 140/456 - (30%)

  Fly    33 VVNTILEAISAEAIDLDENGAEAGGSKPMEEAEADLDHAEEAEEEEEDDEDKYFIDDEGNCYIKT 97
            |.|::|:  |:...::..||: |||                             :.:..:||.:|
  Fly   225 VGNSLLQ--SSGGNNIGSNGS-AGG-----------------------------VANAASCYYET 257

  Fly    98 TPKKQKELQKKLKQAAAKPGKATRSVVSTATNKSINLRPAKSTPKATTSKPPPEPKAISVRP--- 159
            :          ...||..|..|.....|.:.|.|:|:..............|.:...::..|
  Fly   258 S----------AGTAAPPPPPAAAMYPSMSVNVSMNMTMHHGYGAGDAGGVPMQCSQMNWTPPSN 312

  Fly   160 -ARAAAAKAKQSAMPPP-------PALVV-------KVPAPRGRPRKNPVI----PKPEPMDLER 205
             ..||||.|..:.:.||       ||...       :.|||.|.....|:.    ..|.|
  Fly   313 STSAAAAAAAVNVLYPPLLSPGHYPASATYSFTADFRAPAPTGLGALPPLTVGEKESPSP----- 372

  Fly   206 ELEELVDEPDISSMV----TELSD--YT---VDEAAVEAATATLTPNEAEVYEFEDNATTEDENA 261
                    |..||:.    |.:.:  ||   ....:.:||...|:     :..|||.   ||.|.
  Fly   373 --------PANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLS-----LSAFEDE---EDSNE 421

  Fly   262 DKKDVDFVLSNKEVKLKTASSTSQNSNASGHKYSCPHCPYTASKKFLITRHSRSHDVEPSFKCSI 326
            | .|.|...|..|:|                                           |:. |.:
  Fly   422 D-LDGDEGSSGGEMK-------------------------------------------PNL-CRL 441

  Fly   327 CERSFRSNVGLQNHINTHMGNKPHKCKLCESAFTTSGELVRHTRYKHTKEKPHKCTECTYASVEL 391
            |.:::.....|:.|:.||.|.:|::|..|..:|:.:..|..|.| .||.:||.:|..|.....:.
  Fly   442 CGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQAANLTAHVR-THTGQKPFRCPICDRRFSQS 505

  Fly   392 TKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLI 456
            :.:..||..|:|||||:|..|..:..|...|.:|:.||:|||.|||.:|..||:||.:|..|..:
  Fly   506 SSVTTHMRTHSGERPYRCSSCKKSFSDSSTLTKHLRIHSGEKPYQCKLCLLRFSQSGNLNRHMRV 570

  Fly   457 H 457
            |
  Fly   571 H 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTCF	NP_648109.1	FAP	116..>202	CDD:429334	24/107 (22%)
		C2H2 Zn finger	296..316	CDD:275368	0/19 (0%)
		COG5048	321..>621	CDD:227381	49/137 (36%)
		C2H2 Zn finger	324..344	CDD:275368	4/19 (21%)
		C2H2 Zn finger	352..373	CDD:275368	6/20 (30%)
		C2H2 Zn finger	381..401	CDD:275368	4/19 (21%)
		zf-H2C2_2	394..415	CDD:463886	10/20 (50%)
		C2H2 Zn finger	409..429	CDD:275368	5/19 (26%)
		zf-H2C2_2	422..446	CDD:463886	13/23 (57%)
		C2H2 Zn finger	437..457	CDD:275368	8/19 (42%)
		C2H2 Zn finger	467..485	CDD:275368
		C2H2 Zn finger	496..516	CDD:275370
		C2H2 Zn finger	524..544	CDD:275368
		zf-H2C2_2	536..561	CDD:463886
		C2H2 Zn finger	552..573	CDD:275368
		zf-C2H2	587..609	CDD:395048
		C2H2 Zn finger	589..609	CDD:275368
gl	NP_001262708.1	COG5048	<426..571	CDD:227381	53/189 (28%)
		C2H2 Zn finger	439..459	CDD:275368	4/19 (21%)
		C2H2 Zn finger	467..487	CDD:275368	6/20 (30%)
		C2H2 Zn finger	495..515	CDD:275368	4/19 (21%)
		C2H2 Zn finger	523..543	CDD:275368	5/19 (26%)
		C2H2 Zn finger	551..571	CDD:275368	8/19 (42%)