Protein Alignment CTCF and Zfp524

DIOPT Version :9

• Sequence 1: NP_648109.1
• Gene: CTCF / 38817
• FlyBaseID: FBgn0035769
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001102375.1
• Gene: Zfp524 / 365179
• RGDID: 1565485
• Length: 314
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 80/342 - (23%)
• Similarity: 108/342 - (31%)
• Gaps: 132/342 - (38%)

  Fly   136 PAKSTPKATTSKP----PPEPKAISVRPARAAAAKAKQSAMPPPPALVVKVPAPRGRPRKNPVIP 196
            |..||......||    ||.|:....||..||....:        .|...:|..||||
  Rat     8 PLPSTLSGEEEKPLALLPPVPRGRRGRPPGAATTSNR--------TLKSSLPRKRGRP------- 57

  Fly   197 KPEPMDLERELEELVDEPDISSMVTELSD----YTVDEAAVEAATATLTPNEAEVYEFEDNATTE 257
             |..:. |..|...||....|.::. :.|    |||.|
  Rat    58 -PRSVQ-ETPLTAAVDSSGSSDLLL-IDDQGVPYTVPE--------------------------- 92

  Fly   258 DENADKKDVDFVLSNKEVKLKTASSTSQNSNASGHKYSCPHCPYTASKKFLITRHSRSHDVEPSF 322
                                   .|.:.....||.|
  Rat    93 -----------------------GSAADGPQGSGSK----------------------------- 105

  Fly   323 KCSICERSFRSNVGLQNHINTHMGNKPHKCKLCESAFTTSGELVRHTRYKHTKEKPHKCTECTYA 387
                                    ..||.|.:|..||....:|.||: ..|::.|||.|.:|...
  Rat   106 ------------------------RAPHFCPVCLRAFPYLSDLERHS-ISHSELKPHVCKDCGKT 145

  Fly   388 SVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKA 452
            ....:.||||...|.|.||::|..|....::..:|..|..||:||:.|||..|:.|||::|:|:.
  Rat   146 FKRSSHLRRHCNIHAGLRPFRCVLCPRRFREAGELAHHHRIHSGERPYQCPSCRVRFTEANTLRR 210

  Fly   453 H-KLIH-SVVDKPVFQC 467
            | |..| .:|..||..|
  Rat   211 HYKRKHPELVGMPVRLC 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTCF	NP_648109.1	23ISL	<116..206	CDD:293226	20/73 (27%)
		C2H2 Zn finger	296..316	CDD:275368	0/19 (0%)
		COG5048	321..>621	CDD:227381	47/149 (32%)
		zf-C2H2	322..344	CDD:278523	0/21 (0%)
		C2H2 Zn finger	324..344	CDD:275368	0/19 (0%)
		zf-H2C2_2	337..361	CDD:290200	6/23 (26%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
		C2H2 Zn finger	381..401	CDD:275368	6/19 (32%)
		zf-H2C2_2	394..415	CDD:290200	10/20 (50%)
		C2H2 Zn finger	409..429	CDD:275368	4/19 (21%)
		zf-H2C2_2	422..446	CDD:290200	12/23 (52%)
		C2H2 Zn finger	437..457	CDD:275368	9/20 (45%)
		C2H2 Zn finger	467..485	CDD:275368	1/1 (100%)
		C2H2 Zn finger	496..516	CDD:275370
		C2H2 Zn finger	524..544	CDD:275368
		zf-H2C2_2	536..561	CDD:290200
		C2H2 Zn finger	552..573	CDD:275368
		zf-C2H2	587..609	CDD:278523
		C2H2 Zn finger	589..609	CDD:275368
Zfp524	NP_001102375.1	COG5048	<102..218	CDD:227381	46/169 (27%)
		C2H2 Zn finger	111..131	CDD:275368	7/20 (35%)
		zf-H2C2_2	123..148	CDD:290200	9/25 (36%)
		C2H2 Zn finger	139..159	CDD:275368	6/19 (32%)
		zf-H2C2_2	151..174	CDD:290200	10/22 (45%)
		C2H2 Zn finger	167..187	CDD:275368	4/19 (21%)
		zf-H2C2_2	179..203	CDD:290200	11/23 (48%)
		C2H2 Zn finger	195..216	CDD:275368	9/20 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100