DRSC/TRiP Functional Genomics Resources

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Protein Alignment CTCF and CG17568

DIOPT Version :9

Sequence 1:NP_648109.1 Gene:CTCF / 38817 FlyBaseID:FBgn0035769 Length:818 Species:Drosophila melanogaster
Sequence 2:NP_609951.2 Gene:CG17568 / 35198 FlyBaseID:FBgn0032763 Length:513 Species:Drosophila melanogaster


Alignment Length:554 Identity:118/554 - (21%)
Similarity:204/554 - (36%) Gaps:125/554 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 RRTKKDEDPEDLQTFLNNFHKEIEGNSDEKVVNTI---------LE------------AISAEAI 46
            |...||:...:::..:|   :..:||.|..::..|         ||            .:.:|.|
  Fly    12 RLCAKDDAHGNVKVQMN---ENSQGNWDNVLIMAIRKYFEVQMQLEDELSSVLCTECYTLISELI 73

  Fly    47 DLDENGAEAGGSKPMEEAEADLDHAEEAEEEEED----DEDKYFIDDEGNCYIKTTPKKQKELQK 107
            |..|:..:      :::....|...|...::|.|    .:.....||:....||..|..:.|   
  Fly    74 DFAEHVTK------VQDIFEVLRRTETDGDQEMDVAALRQQFGLCDDDWTHIIKPIPALEME--- 129

  Fly   108 KLKQAAAKPGKATRSVVSTATNKSINLRPA---KSTPKATTSKPPPEPKAISVRPARAAAAKAKQ 169
                                 :.::..:||   |..|.|.||....|   ||.|.......:.|:
  Fly   130 ---------------------SDNVYQKPAELLKDFPLAETSSQEME---ISKRTTTTHLIQTKK 170

  Fly   170 SAMPPPPALVVKVPAPRGRPRKNPVIPKPE-----PMDLERELEELVDEPDISSMVTELSDYTVD 229
            :.                    ...|||.|     |:.||:...:|    |:..::.||....:.
  Fly   171 NV--------------------EMEIPKQEFIDLGPILLEKNTSQL----DMEDVLDELPQEELS 211

  Fly   230 EAAVEAATATLTPNEAEVYEFEDNATTEDENADKKDVDFVLSNKEVKLKTASSTSQNS------- 287
            :..:::.|:..:        .|::..:|..::.:.|.||:..:.::....|.:|:.|:       
  Fly   212 QPRLDSTTSPAS--------MENDVKSEMLDSCEGDDDFLPVDGQLMDLVAVATTPNTLESTAEE 268

  Fly   288 NASGHKYSCPHCPYTASKKFLITRH--SRSHDVEPSFK-------CSICERSFRSNVGLQNH-IN 342
            .|...:..|..|......:....:|  .....:|...|       |.||.::..|...|:.| ..
  Fly   269 KAKRGRMDCEKCGKVYRNRASYEKHLERECRRIERRVKVDKTTTTCDICNKTLSSATALKLHKEG 333

  Fly   343 THMGNKPHKCKLCESAFTTSGELVRHTRYKHTKEKPHKCTECTYASVELTKLRRHMTCHTGERPY 407
            .|...||:.|..|.....|...|..| :..||:.:|.:||.|........:|:.|...| .|..:
  Fly   334 IHQNVKPYICDSCGKQLKTITALNEH-KLVHTESRPFECTVCKAGFKNRARLKAHYQIH-AEPSF 396

  Fly   408 QCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPT 472
            .|..|....|.......|.|:||.|::.:||:|.:.|.:|.:||.|.|.|:.: :| :.||||..
  Fly   397 VCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGL-RP-YVCNYCGK 459

  Fly   473 TCGRKADLRVHIKHMHTSDVPMTCRRCGQQLPDR 506
            :....|:.|.|....|..:|.   :..|.:||.|
  Fly   460 SFACNANCRSHKLKKHPQEVQ---QEDGARLPSR 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CTCFNP_648109.1 23ISL <116..206 CDD:293226 19/97 (20%)
C2H2 Zn finger 296..316 CDD:275368 3/21 (14%)
COG5048 321..>621 CDD:227381 57/194 (29%)
zf-C2H2 322..344 CDD:278523 7/29 (24%)
C2H2 Zn finger 324..344 CDD:275368 6/20 (30%)
zf-H2C2_2 337..361 CDD:290200 7/24 (29%)
C2H2 Zn finger 352..373 CDD:275368 5/20 (25%)
C2H2 Zn finger 381..401 CDD:275368 5/19 (26%)
zf-H2C2_2 394..415 CDD:290200 6/20 (30%)
C2H2 Zn finger 409..429 CDD:275368 5/19 (26%)
zf-H2C2_2 422..446 CDD:290200 9/23 (39%)
C2H2 Zn finger 437..457 CDD:275368 9/19 (47%)
C2H2 Zn finger 467..485 CDD:275368 7/17 (41%)
C2H2 Zn finger 496..516 CDD:275370 4/11 (36%)
C2H2 Zn finger 524..544 CDD:275368
zf-H2C2_2 536..561 CDD:290200
C2H2 Zn finger 552..573 CDD:275368
zf-C2H2 587..609 CDD:278523
C2H2 Zn finger 589..609 CDD:275368
CG17568NP_609951.2 zf-AD 10..87 CDD:214871 14/83 (17%)
COG5048 <313..471 CDD:227381 49/161 (30%)
C2H2 Zn finger 314..335 CDD:275368 6/20 (30%)
C2H2 Zn finger 343..363 CDD:275368 5/20 (25%)
C2H2 Zn finger 371..391 CDD:275368 5/19 (26%)
C2H2 Zn finger 398..418 CDD:275368 5/19 (26%)
C2H2 Zn finger 426..446 CDD:275368 9/19 (47%)
zf-H2C2_2 439..463 CDD:290200 10/25 (40%)
C2H2 Zn finger 454..475 CDD:275368 7/20 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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