Protein Alignment CTCF and LOC3291053

DIOPT Version :10

• Sequence 1: NP_648109.1
• Gene: CTCF / 38817
• FlyBaseID: FBgn0035769
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_061506547.1
• Gene: LOC3291053 / 3291053
• VectorBaseID: AGAMI1_011811
• Length: 879
• Species: Anopheles gambiae
• Alignment Length: 863
• Identity: 209/863 - (24%)
• Similarity: 333/863 - (38%)
• Gaps: 191/863 - (22%)

  Fly     8 DEDPEDLQTFLNNFHKEIEGNSDEKVVNTILEAISAEAIDL------DENGAEAGGSKPMEEAEA 66
            |::.::|. |.....::..|:.:...:|...||.:...|.:      .|:.:..|.|...:|.|:
Mosquito   115 DDESKELM-FTGPVSEKANGSKNGMTLNISGEAATVYRITMGDTQESSEDDSSDGKSSIADEDES 178

  Fly    67 DLDHAEEAEEEE--EDDEDKYFIDDEGNCYIKTTPKKQKELQKKLKQAAAKPGKATRSVVSTATN 129
            ..|..|:.||::  .||.|    |...:|                ...::....::.:|.|....
Mosquito   179 TDDSTEDDEEDDCCSDDTD----DSSTSC----------------SSTSSTGASSSETVASLRLE 223

  Fly   130 KSINLRPAKSTPKATTSKPPPEPKAISVRPARAAAAKAKQSAMPPPPALVVKVP----------- 183
            :.|.                        |.|..::.....:.|..|  |:..:|
Mosquito   224 EHIK------------------------RGAEDSSVDLYSTYMDGP--LMQNLPEGSLLQGVGDD 262

  Fly   184 -APRGR---PRKNPVIPKPEPMDLERELEELVDEPDISSMV-------TELSDYTVDEAAVEAAT 237
             .|.|.   |.|..:....||:.::....::.|:.:::..:       ::..:.:..|:..:.:.
Mosquito   263 YVPEGDRIFPEKELMNDVLEPLQMDEPTSKIEDKVELAKPLQCEEQQRSQQQEQSQQESCQQESE 327

  Fly   238 ATLTPNEAEVYEFEDNATTEDENAD---KKDVDFVLSNKEVKLKTASSTSQNSNASGHKYSCPHC 299
            ....|....  :.:.....|||..|   ||      |.|..|..|.|:      |....|.|..|
Mosquito   328 EQEKPTPRN--DDDQQGHEEDEKNDGVPKK------SRKRKKRSTGSA------AQAKNYVCLVC 378

  Fly   300 PYTASKKFLITRHSRSHDVEPSFKCSICERSFRSNVGLQNHINTHMGNKPHKCKLCESAFTTSGE 364
            ....||...:..|:|:|..|..:.|.||.:||.....|..|...|...||..|::|...:|::|.
Mosquito   379 QKRFSKAIYLKVHTRTHTGEKPYACDICFKSFTQASSLNTHKRLHFNVKPFVCEICNQQYTSAGN 443

  Fly   365 LVRHTRYKHTKEKPHKCTECTYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHMVIH 429
            ...|.| .||:|||:.|:.|.....:.:..:.|...|:.|:||.|..|..|..::..|..||.||
Mosquito   444 YKVHLR-THTQEKPYACSYCDKRFSQHSSKKMHERVHSQEKPYPCQVCLKAFSNVSNLTVHMRIH 507

  Fly   430 TGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPTTCGRKADLRVHIKHMHTSDVPM 494
            .|.|.|:||.|...|.||.:||.| .|.:..|...|||:.||.:....::|..| ||.|..:.|.
Mosquito   508 QGLKPYKCDKCDKSFAQSQTLKTH-YISAHTDVRPFQCDRCPKSYATLSNLNNH-KHTHLEEKPF 570

  Fly   495 TCRRCGQQLPDRYQYKLHVKSHEGEKCYSCKLCSYASVTQRHLASHML-IHLDEKPFHCDQCPQA 558
            .|..||::...:...|.|..||..|:.|.|:.|:.:..||..|.:|.. :|..|:||.|.:|.::
Mosquito   571 ACEECGKRFTQKSSLKTHALSHNTERPYPCEECTKSFNTQAMLNTHRRNMHSTERPFACTKCNKS 635

  Fly   559 FRQRQLLRRHMNLVHNEE--------------------YQPPEPREKLHKCPSCPREFTHKGNLM 603
            :.|...||:|| |.|.|.                    :|.....||.:.||:|.:.|:.:.:|.
Mosquito   636 YAQETRLRQHM-LSHAEVKPYPCVECGKTFTTATNLRIHQRVHSGEKPYPCPTCGKCFSQRSSLR 699

  Fly   604 RHMETH-------DDSANAREKRRRLKLGRNVRLQKDGTVITLIKDQYVDMDRD--QEENEEDDN 659
            .|...|       :.|..:...|.|.|....:...:.|.|.|| :.:|.:..:.  |.:.::.|:
Mosquito   700 THEILHLPPELRPEPSVQSDIPRGRRKQKIKIECGECGKVFTL-RGRYRNHMKQVHQRDVQDVDD 763

  Fly   660 PESYDLAEIEPENSEAEDADDDVETIVSDPIRQRIKPAPIIINKQARLAASEKQPMIINQRLRSQ 724
            .:...|     |.||..|.|..::|.|...:.|                  |||    || |||.
Mosquito   764 EKCMSL-----EASEESDNDAPIDTEVGTKVVQ------------------EKQ----NQ-LRSA 800

  Fly   725 RGTKTFHIKEEPDNSDFTVEWQGDDGEVMVVELVNGDEEVLVKHEPSANSKISAKNCFGFEDDDD 789
            .|..    :...|.|......:.|:           |:|.   ||               |||:|
Mosquito   801 SGNN----RSGKDLSQHLSAAEEDE-----------DDET---HE---------------EDDED 832

  Fly   790 YE-EYGDGENEVDGASQE 806
            || ||.|..|:.|...:|
Mosquito   833 YEDEYEDDGNDDDEEDRE 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTCF	NP_648109.1	FAP	116..>202	CDD:429334	15/100 (15%)
		C2H2 Zn finger	296..316	CDD:275368	6/19 (32%)
		COG5048	321..>621	CDD:227381	102/327 (31%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..373	CDD:275368	6/20 (30%)
		C2H2 Zn finger	381..401	CDD:275368	3/19 (16%)
		zf-H2C2_2	394..415	CDD:463886	7/20 (35%)
		C2H2 Zn finger	409..429	CDD:275368	6/19 (32%)
		zf-H2C2_2	422..446	CDD:463886	12/23 (52%)
		C2H2 Zn finger	437..457	CDD:275368	9/19 (47%)
		C2H2 Zn finger	467..485	CDD:275368	5/17 (29%)
		C2H2 Zn finger	496..516	CDD:275370	5/19 (26%)
		C2H2 Zn finger	524..544	CDD:275368	6/20 (30%)
		zf-H2C2_2	536..561	CDD:463886	8/25 (32%)
		C2H2 Zn finger	552..573	CDD:275368	8/20 (40%)
		zf-C2H2	587..609	CDD:395048	6/21 (29%)
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
LOC3291053	XP_061506547.1	None