Protein Alignment CTCF and Zfp933

DIOPT Version :10

• Sequence 1: NP_648109.1
• Gene: CTCF / 38817
• FlyBaseID: FBgn0035769
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_941021.1
• Gene: Zfp933 / 242747
• MGIID: 1922865
• Length: 468
• Species: Mus musculus
• Alignment Length: 326
• Identity: 118/326 - (36%)
• Similarity: 164/326 - (50%)
• Gaps: 22/326 - (6%)

  Fly   289 ASGHK-YSCPHCPYTASKKFLITRHSRSHDVEPSFKCSICERSFRSNVGLQNHINTHMGNKPHKC 352
            |.|.| |.|..|....:....:.||.|:|..|..:||:.|:::|..|..|..|..||.|.||::|
Mouse   125 AIGEKPYECNQCGKAFTYHSQLRRHKRTHTGEKPYKCNQCDKAFSQNGHLIIHKRTHTGEKPYEC 189

  Fly   353 KLCESAFTTSGELVRHTRYKHTKEKPHKCTECTYASVELTKLRRHMTCHTGERPYQCPHCTYASQ 417
            ..|..|||...:|..|.| .||.|||:||.:|..|.::...||.|...||||:||:|..|..|
Mouse   190 NQCGKAFTDQSQLRIHKR-AHTGEKPYKCNQCDKAFLQNINLRIHKRAHTGEKPYKCNQCDKA-- 251

  Fly   418 DMFKLKRHMVI----HTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPTTCGRKA 478
              |....|::|    |||||.|:|:.|...|...:.|:.|:.||: .:|| ::||.|.....:.:
Mouse   252 --FAQNGHLIIHKRTHTGEKPYECNQCGKAFADQSQLRIHRRIHT-GEKP-YKCNQCDKAFAQHS 312

  Fly   479 DLRVHIKHMHTSDVPMTCRRCGQQLPDRYQYKLHVKSHEGEKCYSCKLCSYASVTQRHLASHMLI 543
            :||:| |..||.:.|..|.:|.:........|:|.::|.|||.|.|..|..|.....||..|..|
Mouse   313 NLRIH-KRTHTGEKPYECNQCDKAFLQNINLKIHKRAHTGEKSYECSQCGKAFARYYHLQCHERI 376

  Fly   544 HLDEKPFHCDQCPQAFRQRQLLRRHMNLVHNEEYQPPEPREKLHKCPSCPREFTHKGNLMRHMET 608
            |.:|||:.|:||.:.|.|...|:.|.. .|.        .||.:.|..|.:.|....:|.||..|
Mouse   377 HTEEKPYKCNQCDKVFSQSHSLQIHKR-THT--------GEKPYVCNQCGKAFADNSHLRRHKRT 432

  Fly   609 H 609
            |
Mouse   433 H 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTCF	NP_648109.1	FAP	116..>202	CDD:429334
		C2H2 Zn finger	296..316	CDD:275368	5/19 (26%)
		COG5048	321..>621	CDD:227381	107/293 (37%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..373	CDD:275368	8/20 (40%)
		C2H2 Zn finger	381..401	CDD:275368	6/19 (32%)
		zf-H2C2_2	394..415	CDD:463886	11/20 (55%)
		C2H2 Zn finger	409..429	CDD:275368	6/23 (26%)
		zf-H2C2_2	422..446	CDD:463886	11/27 (41%)
		C2H2 Zn finger	437..457	CDD:275368	5/19 (26%)
		C2H2 Zn finger	467..485	CDD:275368	6/17 (35%)
		C2H2 Zn finger	496..516	CDD:275370	4/19 (21%)
		C2H2 Zn finger	524..544	CDD:275368	6/19 (32%)
		zf-H2C2_2	536..561	CDD:463886	12/24 (50%)
		C2H2 Zn finger	552..573	CDD:275368	7/20 (35%)
		zf-C2H2	587..609	CDD:395048	6/21 (29%)
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
Zfp933	NP_941021.1	KRAB	4..44	CDD:460171
		C2H2 Zn finger	109..125	CDD:275368	118/326 (36%)
		C2H2 Zn finger	133..153	CDD:275368	5/19 (26%)
		COG5048	157..>467	CDD:227381	107/294 (36%)
		C2H2 Zn finger	161..181	CDD:275368	6/19 (32%)
		C2H2 Zn finger	189..209	CDD:275368	8/20 (40%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	6/23 (26%)
		C2H2 Zn finger	273..293	CDD:275368	5/19 (26%)
		C2H2 Zn finger	301..321	CDD:275368	7/20 (35%)
		C2H2 Zn finger	329..349	CDD:275368	4/19 (21%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	385..405	CDD:275368	7/20 (35%)
		C2H2 Zn finger	413..433	CDD:275368	6/19 (32%)
		C2H2 Zn finger	441..461	CDD:275368