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Protein Alignment CTCF and ZNF420

DIOPT Version :10

Sequence 1:	NP_648109.1	Gene:	CTCF / 38817	FlyBaseID:	FBgn0035769	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001316444.1	Gene:	ZNF420 / 147923	HGNCID:	20649	Length:	704	Species:	Homo sapiens

Alignment Length:	418	Identity:	129/418 - (30%)
Similarity:	197/418 - (47%)	Gaps:	26/418 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 MDLERELEELVD--EPDI--SSMVTELSDYTVDEAAVEAATATLTPNEAEVYEFEDNATTEDENA 261
            :|..:|..|.:|  :.|:  ..|:...|:....:.....|:..|:| |...||.|   .::.|.:
Human    13 IDFSQEEWECLDSAQRDLYRDVMLENYSNLVSLDLPSRCASKDLSP-EKNTYETE---LSQWEMS 73

  Fly   262 DK-KDVDFVLSNKEVKLKTASSTSQNSNASGHKYSCPHCPYTASKKF----LITRHSRSHDVEPS 321
            |: ::.|...||....|:......:........:......|.....|    .:::|||.|..|..
Human    74 DRLENCDLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMSIFNQHTYLSQHSRCHSTEKP 138

  Fly   322 FKCSICERSFRSNVGLQNHINTHMGNKPHKCKLCESAFTTSGELVRHTRYKHTKEKPHKCTECTY 386
            :||..|.::||....|..|.:.|.|.||::||.|..||:...:|..|.|. ||.|||:.|.||..
Human   139 YKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRL-HTGEKPYACKECGK 202

  Fly   387 ASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLK 451
            |..:.::|..|...||||:||:|..|..|.....:|.||..:|||||.|:|..|...|||::.|.
Human   203 AFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYECKECGKAFTQNSQLT 267

  Fly   452 AHKLIHSVVDKPVFQCNYCPTTCGRKADLRVHIKHMHTSDVPMTCRRCGQQLPDRYQYKLHVKSH 516
            .|:.:|:  .:.:::|..|.....:.:.|.:| |.:||.:.|..|:.||:......|...|.|.|
Human   268 LHQRLHT--GEKLYECKECRKVFTQLSQLILH-KRIHTGEKPYECKECGKAFICGSQLSQHQKIH 329

  Fly   517 EGEKCYSCKLCSYASVTQRHLASHMLIHLDEKPFHCDQCPQAFRQRQLLRRHMNLVHNEEYQPPE 581
            .|||.|.||.|..|.:....|..|..||..|||:.|::|.:||.:...|.:|..:..|
Human   330 NGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTN------- 387

  Fly   582 PREKLHKCPSCPREFTHKGNLMRHMETH 609
              ||.::|..|.:.|:|...|.:|...|
Human   388 --EKPYECKECGKMFSHGSQLTQHQRIH 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.