Protein Alignment CTCF and znf142

DIOPT Version :10

• Sequence 1: NP_648109.1
• Gene: CTCF / 38817
• FlyBaseID: FBgn0035769
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_002934000.3
• Gene: znf142 / 100485110
• XenbaseID: XB-GENE-1032931
• Length: 1898
• Species: Xenopus tropicalis
• Alignment Length: 655
• Identity: 154/655 - (23%)
• Similarity: 244/655 - (37%)
• Gaps: 157/655 - (23%)

  Fly    23 KEIEGNSDEKVVNTILEAISAEAIDLDENGAEAGGSKPMEEAEADLDHAEEAEEEEEDDEDK--- 84
            :|:.|||.|..:...|...|..::|                        ||::..|||::.:
 Frog  1288 RELRGNSSETALRRHLRERSVSSVD------------------------EESQNTEEDEDHRKEF 1328

  Fly    85 -YFIDDEGNCYIKTTP---KKQKELQKKLKQAAAKPGK------ATRSVVSTATNKSINLRPAKS 139
             |.||.|......:.|   .:.:.::..:|:...|||:      :.|.:.|.|..:...|....|
 Frog  1329 VYKIDGESRISCPSCPFTCSQNRAMRTHMKKGCLKPGELQCPLCSFRCMSSAALKRHKELHQKYS 1393

  Fly   140 TPKAT--------TSKPPPEPKAISVRPARAAAAKAKQSAMPPPPALVVKVPAPRGRPRKNPVIP 196
            ..:|.        |.|   :|:.:            ||.         ||:       |...|.|
 Frog  1394 CNRAQLKCKQCDFTCK---QPRCM------------KQH---------VKI-------RHEGVKP 1427

  Fly   197 -KPEPMDLERELEELVDEPDISSMVTELSDYTVDEAAVEAAT-ATLTPNEAEVYE---------- 249
             :.:..|........:|..:  |:.|.:...:.|..:....| :.|..::..|:|
 Frog  1428 HRCQYCDFSTTRRYRLDAHE--SLHTGVGRISCDSCSRTFGTNSKLRLHQRRVHEKKPTHFCSLC 1490

  Fly   250 ----FEDN-------ATTEDENADKKDVDFVLSNKEVKLKTASSTSQNSNASGHKYSCPHCPYTA 303
                :..|       :....|.|...||.....:.|..||..|.......|:   :.|..|.::.
 Frog  1491 DYSGYSQNDIARHMGSCHNGEPAFPCDVCQASFSSEAALKQHSLRKHQEKAT---HECLQCQFSC 1552

  Fly   304 SKKFLITRHSRSHDVEPSFKCSICERSFRSNVGLQNHINTHMGNKPHKCKLCESAFTTSGELVRH 368
            .....:..|.:.|.::  ..|:||:::|.....|:.|..:|..   |.|.||:.|.....:||.|
 Frog  1553 HSLATLRCHLQKHHLQ--LDCTICKQTFCRRQDLEEHRKSHFA---HHCHLCQYAAKDRQQLVHH 1612

  Fly   369 TRYKHTKEKP---------------------------------------HKCTECTYASVELTKL 394
              |....|.|                                       :||::|.|.:....|:
 Frog  1613 --YAEEHETPAVPGAEQEMGLLCCPFCSFSCRHQLVYDHHVKGHGGIRVYKCSDCEYTTKNKQKI 1675

  Fly   395 RRHMTCHTGERPYQCPHCTYASQDMFKLKRHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSV 459
            ..|...||||:||:|..|:||..|..:||.||.||..||||.|..|..:....|.||.|...|:.
 Frog  1676 TWHSRIHTGEKPYKCHLCSYACADPSRLKYHMRIHKDEKKYLCPECGYKCKWVNQLKYHMTKHTG 1740

  Fly   460 VDKPVFQCNYCPTTCGRKAD-LRVHIKHMHTSDVPMTCRRCGQQLPDRYQYKLHVKSHEGEKCYS 523
            : || :||..| ..|..:|| ||||.:..|.......|.:||:....|:..|.|::.|..||.|.
 Frog  1741 L-KP-YQCEEC-DYCTNRADALRVHRETRHREVRSFICEQCGKAFKTRFLLKTHMRKHSEEKPYV 1802

  Fly   524 CKLCSYASVTQRHLASHMLIHLDEKPFHCDQCPQAFRQRQLLRRHMNLVHNEEYQPPEPREKLHK 588
            |.||..:......|..|.|.|.::.||.|..|....:|:..:.:|:...|.::   |:..:.:.|
 Frog  1803 CNLCQRSFRWPAGLRHHYLTHTNQHPFFCQYCTYRAKQKFQVVKHLQRHHPDQ---PDIAKGVGK 1864

  Fly   589 CPSCP 593
            .|..|
 Frog  1865 DPFVP 1869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTCF	NP_648109.1	FAP	116..>202	CDD:429334	18/100 (18%)
		C2H2 Zn finger	296..316	CDD:275368	3/19 (16%)
		COG5048	321..>621	CDD:227381	93/313 (30%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..373	CDD:275368	8/20 (40%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		zf-H2C2_2	394..415	CDD:463886	9/20 (45%)
		C2H2 Zn finger	409..429	CDD:275368	9/19 (47%)
		zf-H2C2_2	422..446	CDD:463886	12/23 (52%)
		C2H2 Zn finger	437..457	CDD:275368	6/19 (32%)
		C2H2 Zn finger	467..485	CDD:275368	9/18 (50%)
		C2H2 Zn finger	496..516	CDD:275370	6/19 (32%)
		C2H2 Zn finger	524..544	CDD:275368	6/19 (32%)
		zf-H2C2_2	536..561	CDD:463886	8/24 (33%)
		C2H2 Zn finger	552..573	CDD:275368	4/20 (20%)
		zf-C2H2	587..609	CDD:395048	3/7 (43%)
		C2H2 Zn finger	589..609	CDD:275368	2/5 (40%)
znf142	XP_002934000.3	C2H2 Zn finger	358..378	CDD:275368
		C2H2 Zn finger	386..406	CDD:275368
		C2H2 Zn finger	414..431	CDD:275368
		C2H2 Zn finger	448..468	CDD:275368
		C2H2 Zn finger	534..555	CDD:275368
		C2H2 Zn finger	563..584	CDD:275368
		C2H2 Zn finger	592..612	CDD:275368
		C2H2 Zn finger	620..640	CDD:275368
		C2H2 Zn finger	648..668	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	703..720	CDD:275368
		C2H2 Zn finger	1401..1422	CDD:275368	7/51 (14%)
		C2H2 Zn finger	1430..1450	CDD:275368	3/21 (14%)
		C2H2 Zn finger	1458..1476	CDD:275368	3/17 (18%)
		C2H2 Zn finger	1516..1537	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1545..1565	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1571..1591	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1634..1654	CDD:275368	0/19 (0%)
		C2H2 Zn finger	1662..1682	CDD:275368	5/19 (26%)
		SFP1	<1684..1739	CDD:227516	25/54 (46%)
		C2H2 Zn finger	1690..1710	CDD:275368	9/19 (47%)
		C2H2 Zn finger	1718..1738	CDD:275368	6/19 (32%)
		zf-H2C2_2	1731..1755	CDD:463886	10/26 (38%)
		C2H2 Zn finger	1746..1767	CDD:275368	9/21 (43%)
		C2H2 Zn finger	1775..1795	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1803..1823	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1831..1851	CDD:275368	4/19 (21%)