DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment qm and PDSS1

DIOPT Version :9

Sequence 1:	NP_001163370.1	Gene:	qm / 38816	FlyBaseID:	FBgn0019662	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_055132.2	Gene:	PDSS1 / 23590	HGNCID:	17759	Length:	415	Species:	Homo sapiens

Alignment Length:	248	Identity:	55/248 - (22%)
Similarity:	111/248 - (44%)	Gaps:	22/248 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 IVQMLHNSSLLIDDIEDNSILRRGVPVAHSIYGVASTINAANYALFLALEKVQQLDHPEATKVYT 128
            |.:|:|.:||:.||:.|::..|||....:.|:|....:.|.:..|..|...:.::.:.....:.|
Human   168 IAEMIHTASLVHDDVIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILT 232

  Fly   129 EQLLELHRGQGMEIYWRDSFTCPSESD----YKLMTVRKTGGLFMLAIRLMQLFSSNKE------ 183
            :.:.:|.||:.:::..::     :|::    |...|.:||..|...:.:.:.:......
Human   233 QVIEDLVRGEFLQLGSKE-----NENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHEIA 292

  Fly   184 -DYSKLTAILGLYFQIRDDYCNLSLKEYTENKSFAEDLTEGKFGFPVIHAVRTQKQDKQVLHILR 247
             .|.|   .:|:.||:.||..:.:.......|..:.||..|....||:.|  .|:..:....|:|
Human   293 YQYGK---NVGIAFQLIDDVLDFTSCSDQMGKPTSADLKLGLATGPVLFA--CQQFPEMNAMIMR 352

  Fly   248 QRTHDIEVKKYCITLLEKLGSFQYTRKVLESLDAEARSEVARLGSNPYMDRLL 300
            :.:...:|.:....:|:..| .|.|..:.:....||..|:::|..:|..|.|:
Human   353 RFSLPGDVDRARQYVLQSDG-VQQTTYLAQQYCHEAIREISKLRPSPERDALI 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qm	NP_001163370.1	polyprenyl_synt	30..267	CDD:278763	45/213 (21%)
PDSS1	NP_055132.2	PLN02890	6..415	CDD:178478	55/248 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..35
		Isoprenoid_Biosyn_C1	102..413	CDD:294142	55/248 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0142
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810