Protein Alignment Cln7 and ARN2

DIOPT Version :10

• Sequence 1: NP_648107.3
• Gene: Cln7 / 38813
• FlyBaseID: FBgn0035767
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_011816.2
• Gene: ARN2 / 856338
• SGDID: S000001039
• Length: 620
• Species: Saccharomyces cerevisiae
• Alignment Length: 658
• Identity: 131/658 - (19%)
• Similarity: 215/658 - (32%)
• Gaps: 205/658 - (31%)

  Fly    12 ETKR-----------LPEDVDDGLETLEEYKQR---------------------WRSVRIIYFTM 44
            :|||           :.|.:||.....:|.|.:                     |:...|..|:.
Yeast    12 QTKRKNTEKNCNELMVDEKMDDDSSPRDEMKDKLKGTKSLIIRKSELMAKKYDTWQLKAIFLFSA 76

  Fly    45 FL--MALGFSIILTGIW-PY-LNKLDPDAGKEFMGLIV-AANPLGQMIF---SPIFGWWGNKLGK 101
            |:  .|.|....:.|.: .| :|.....:....:.:|| ..:.:.|:||   |.|||
Yeast    77 FICTFAYGLDSSIRGTYMTYAMNSYSAHSLISTVSVIVLMISAVSQVIFGGLSDIFG-------- 133

  Fly   102 IRLPL-LLSLSLFTLASGIYSSLELRPDNVKYWMLSSRF----LIGVSSANIALCRSYLSAATRI 161
             ||.| |:|:.|:.:.:.|.|    :..:|:.:...:.|    |:||....:.:    ||..:.:
Yeast   134 -RLTLFLVSIVLYIVGTIIQS----QAYDVQRYAAGAVFYYVGLVGVMLQVVLM----LSDNSSL 189

  Fly   162 SERTHAVAMVSLAQVLGFIIGPTLQAAVTPLGDQGHVWLWG------------------KMHF-- 206
            ..|.....:.|...::...:..::..|..||.:    |.|.                  .:|.
Yeast   190 KWRLFYTLIPSWPSIITTWVSGSVVEAANPLEN----WSWNIAMWAFIFPLCCIPLILCMLHMRW 250

  Fly   207 ---------------NMYTASGWINVL------MSIGNFMMFLPGVFEEHKIAAREVMVMQGGTS 250
                           :.|...|.:.:|      :.:...::|..||.     .....:.:.||.|
Yeast   251 KVRNDVEWKELQDEKSYYQTHGLVQMLVQLFWKLDVVGVLLFTAGVG-----CILVPLTLAGGVS 310

  Fly   251 EKETWKGIKPSYLSAWTLIVAF---FVLVFNFVLLETLGTSLTMDMFAWSNDEALWY-MGIMM-- 309
              ..|:..|        :|..|   ||||..|:..|:....:....|....|..:|. :|||.
Yeast   311 --TNWRNSK--------IIGPFVLGFVLVPGFIYWESRLALVPFAPFKLLKDRGVWAPLGIMFFI 365

  Fly   310 ------------------------TTAAIVSLVTFV--LIEPMCKIIAER------YVLIWGGFS 342
                                    :...|::|.:||  ::.|...:|..|      |: |:|| |
Yeast   366 CFVYQMAAGYLYTILVVAVDESASSATRIINLYSFVTAVVAPFLGLIVTRSSRLKSYI-IFGG-S 428

  Fly   343 LMFLGRVLFVPW--GPDPPKLAQPFNASWNLSE-----SDPIFLGCPTTQKWCGELPALTLTQFI 400
            |.|:...||..:  |.|...........|.||.     ...:.:...|:.:....:.||..|.|.
Yeast   429 LYFITMGLFYRYRSGQDADGGIIAGMVIWGLSSCLFDYPTIVSIQSVTSHENMATVTALNYTVFR 493

  Fly   401 IGFAFTSIGYPIGVTLIQTIFSKVLGPRPQGVWMGWMTGSGCLSRVLGPVFVGSIYT-RLGTFWT 464
            ||.|..:.  ..|....|:::.|:|.      :||        ...|.....||..| .|...|.
Yeast   494 IGGAVAAA--ISGAIWTQSLYPKLLH------YMG--------DADLATAAYGSPLTFILSNPWG 542

  Fly   465 FGVTSAM-----------MLVSMFWLQCSNRLLIPPTFEKTTPVELKELNKHNGSKLLDDHSPDT 518
            ..|.|||           ::|::        :...|.|..|..|....|.:....||.|.....|
Yeast   543 TPVRSAMVEAYRHVQKYEVIVAL--------VFSAPMFLLTFCVRDPRLTEDFAQKLPDREYVQT 599

  Fly   519 HNGSPPED 526
            ....|..|
Yeast   600 KEDDPIND 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cln7	NP_648107.3	MFS_MFSD8	37..487	CDD:340884	111/560 (20%)
ARN2	NP_011816.2	MFS_ARN_like	69..581	CDD:340880	115/573 (20%)