Protein Alignment Cln7 and QDR2

DIOPT Version :10

• Sequence 1: NP_648107.3
• Gene: Cln7 / 38813
• FlyBaseID: FBgn0035767
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_012145.1
• Gene: QDR2 / 854685
• SGDID: S000001383
• Length: 542
• Species: Saccharomyces cerevisiae
• Alignment Length: 535
• Identity: 109/535 - (20%)
• Similarity: 192/535 - (35%)
• Gaps: 138/535 - (25%)

  Fly    30 YKQRWRSVRIIY--FTMFLMALGFSIILTGI-WPYLNKLDP--DAGKEFMGLIVAANPLGQMIFS 89
            :.:.:::|.|..  ||.|     ||.|...| :|.|:.::.  |..:|.:.:.|....:.|.:..
Yeast    55 FSRSFKTVLIAQCAFTGF-----FSTIAGAIYYPVLSVIERKFDIDEELVNVTVVVYFVFQGLAP 114

  Fly    90 PIFGWWGNKLGKIRLPLLLSLSLFTLASGIYSSLELRPDNVKYWMLSSRFLIGVSSANIALCRSY 154
            ...|.:.:.||: |..:|:::.::   .|....|.......:..:|......|:|.. ||:....
Yeast   115 TFMGGFADSLGR-RPVVLVAIVIY---FGACIGLACAQTYAQIIVLRCLQAAGISPV-IAINSGI 174

  Fly   155 LSAATRISERTHAVAMVSLAQVLGFIIGPTLQAAVTPLGDQGHVWLWGKMHFNMYTASGWINVLM 219
            :...|..:||...|..|:..||||...|..:.|.::..      |.|..:.:.:...||    :.
Yeast   175 MGDVTTRAERGGYVGYVAGFQVLGSAFGALIGAGLSSR------WGWRAIFWFLAIGSG----IC 229

  Fly   220 SIGNFMMFLP----------GVFEEHKIAAREVMVMQGGTSEKETWKGIKPSY------------ 262
            .:.:|:: ||          .|..:..:....::|:   .:.:::.....|.|
Yeast   230 FLASFLI-LPETKRNISGNGSVTPKSYLNRAPILVL---PTVRKSLHLDNPDYETLELPTQLNLL 290

  Fly   263 -----LSAWTLIVAFFVLVFNFVLLETLGTSLTMDMFAWSNDEALWY--MGIMMTTAAIVSLVTF 320
                 |.|:.:.:...|....|.:..|..|:|:.   |.|....|..  :|:....:.|.:|.:.
Yeast   291 APFKILKAYEICILMLVAGLQFAMYTTHLTALST---ALSKQYHLTVAKVGLCYLPSGICTLCSI 352

  Fly   321 VLIEPMCKIIAERYVLIWGGFSLMFLGRVLFVP-W-GPDPPKLAQPFNASWNL----SESDP--- 376
            |        ||.|| |.|.     :..|:.:.. | |....||.:..:...||    .|:||
Yeast   353 V--------IAGRY-LNWN-----YRRRLKYYQNWLGKKRSKLLEEHDNDLNLVQRIIENDPKYT 403

  Fly   377 --IFLG----------------CPTTQKWCGELPA-LTLTQFIIGFA--FTSIGYPIGVTLIQTI 420
              ||..                |  ...||..:.| |.....:.|||  |::.......|||..:
Yeast   404 FNIFKARLQPAFVTLLLSSSGFC--AYGWCITVKAPLAAVLCMSGFASLFSNCILTFSTTLIVDL 466

  Fly   421 FSKVLGPRPQGVWMGWMTGSGCLSR---VLGPVFV------------GSIYTRLGTFWTFGVTSA 470
            |.....           |.:|||:.   :|..||:            |.::|.||     .:||:
Yeast   467 FPTKTS-----------TATGCLNLFRCILSAVFIAALSKMVEKMKFGGVFTFLG-----ALTSS 515

  Fly   471 MMLVSMFWLQCSNRL 485
            ..::....|:....|
Yeast   516 SSILLFILLRKGKEL 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cln7	NP_648107.3	MFS_MFSD8	37..487	CDD:340884	109/528 (21%)
QDR2	NP_012145.1	MFS_Tpo1_MDR_like	64..530	CDD:340881	107/524 (20%)