Protein Alignment Cln7 and AZR1

DIOPT Version :10

• Sequence 1: NP_648107.3
• Gene: Cln7 / 38813
• FlyBaseID: FBgn0035767
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_011740.3
• Gene: AZR1 / 853139
• SGDID: S000003456
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 480
• Identity: 93/480 - (19%)
• Similarity: 176/480 - (36%)
• Gaps: 126/480 - (26%)

  Fly    34 WRSVRIIYFTMFLMALGFSIILTGIWPYLNKLDPDAGKEF-----MGLIVAANPLGQMIFSPIFG 93
            :.|:..:..::||.||...|:.|.|        .:..|:|     :|.:.....|...:.:.|:|
Yeast    67 YASLIALALSLFLAALDIMIVSTII--------EEVAKQFGSYSEIGWLFTGYSLPNALLALIWG 123

  Fly    94 WWGNKLGKIRLPLLLSLSLFTLASGIYSSLELRPDNVKYWMLSSRFLIGVSSANIALCRSYLSAA 158
            .....:| .:..:|.::.:|.:.| :.|:|.    |....::..|.:.||....|. ..|::..:
Yeast   124 RIATPIG-FKETMLFAIVIFEIGS-LISALA----NSMSMLIGGRVIAGVGGCGIQ-SLSFVIGS 181

  Fly   159 TRI--SERTHAVAMVSLAQVLGFIIGPTLQAAVTPLGDQGHVWLWGKMHFNMYTASGWINVLMSI 221
            |.:  |:|...:|::|.:..:..::||.|....|    ....|.|          ..::|  :.|
Yeast   182 TLVEESQRGILIAVLSCSFAIASVVGPFLGGVFT----SSVTWRW----------CFYVN--LPI 230

  Fly   222 GNFMMFL------PGV--FEE-----HKIAAREVMVMQG---------GTSEKETWKGIKPSYLS 264
            |....||      ||:  |:|     .|..::.:.:::.         |.|:...|:  ||
Yeast   231 GGLAFFLFLFFYNPGLSTFQETMDNIRKFPSQFIEIVRNVAYHLLKIKGFSKLNGWR--KP---- 289

  Fly   265 AWTLIVAFFVLVFNFVLLE----TLGTSLTMDMFAWSNDEALWYMGIMMTTAAIVSLVTFVLIEP 325
                   |..|:|.:.::|    :.|.:..:..|.:..:...|      .:|:|:.|.
Yeast   290 -------FMELIFMYDIIEFVFCSAGFTCILLAFTFGGNRYAW------NSASIIILF------- 334

  Fly   326 MCKIIAERYVLIWGGFSLMFLGRVLFVPWGPDPPKLAQPFNASWNLSE------SDPIFLGCPTT 384
               ||....|::.|.:..:...:...|...|.    .||..:..|:.:      :..:||.|
Yeast   335 ---IIGIVLVVLAGIYDFLVFPKFNIVKATPH----YQPLMSWTNIKKPGIFTVNIALFLTC--- 389

  Fly   385 QKWCGELPALTLTQFIIGFAFTSIGYPIGVTLIQTIFSKVLGPRPQGVWMGWMTGSGCLSRVLGP 449
               .|.:...|.........:....:...|.|:..|.|.|:    ..:..|.:|..   :|.:.|
Yeast   390 ---AGYISQFTYIVQYFQLIYNDSAWRAAVHLVACIISTVV----TAILCGAITDK---TRQIKP 444

  Fly   450 VFV-GSIYTRLGTFWTFGVTSAMML 473
            :.| .||         |||..|.:|
Yeast   445 IIVISSI---------FGVVGAGIL 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cln7	NP_648107.3	MFS_MFSD8	37..487	CDD:340884	92/477 (19%)
AZR1	NP_011740.3	MFS_Azr1_MDR_like	83..540	CDD:341045	88/464 (19%)