Protein Alignment Cln7 and mfsd-8.3

DIOPT Version :10

• Sequence 1: NP_648107.3
• Gene: Cln7 / 38813
• FlyBaseID: FBgn0035767
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_001022903.1
• Gene: mfsd-8.3 / 190242
• WormBaseID: WBGene00021814
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 487
• Identity: 134/487 - (27%)
• Similarity: 234/487 - (48%)
• Gaps: 51/487 - (10%)

  Fly    20 VDDGLET-----LEEYKQRWRSVRIIYFTMFLMALGFSIILTGIWPYLNKLDPDAGKEFMGLIVA 79
            :|.|.::     ::..:..|:|:.::........:.|||....:||:||.:||.|...|.|.|.|
 Worm    26 IDSGGKSESDIIIDNRETSWQSIYLLTAIGMFCGIQFSIFFPTLWPFLNTVDPTASASFFGFITA 90

  Fly    80 ANPLGQMIFSPIFGWWGNKLGKIRLPLLLSLSLFTLASGIYSSLELRPDNVKYW-MLSSRFLIGV 143
            |..:||.:.||:||:|.||...:|.||:..:|:..|::.|:..:|...:..:.| |:.:||.|||
 Worm    91 AFSVGQGLASPVFGYWMNKAKSVRQPLVFGISVMILSNIIFCFVEAFAEKERRWVMMVARFFIGV 155

  Fly   144 SSANIALCRSYLSAATRISERTHAVAMVSLAQVLGFIIGPTLQAAVTPLGDQGHVWLWGKMHFNM 208
            .:..|.:.|:|.:.|:.:.:|..|:..:..:.|:|..:||.:|.|.||:|..|  ...|..|.:|
 Worm   156 GAGTIGVMRAYAATASSLKDRARAITFIQASYVIGMTLGPGIQVAFTPIGYPG--LSKGVFHVDM 218

  Fly   209 YTASGWINVLMSIGNFMMFLPGVFEEHKIAAREVMVMQGGTSEKETWKGIKPSY--LSAWTLIVA 271
            ||:..|...::|:.:.:...  :|.|...|..:    ||..:| :::..: |::  :|....::.
 Worm   219 YTSPAWFASIISLLSVIFIF--IFLEENYAGLD----QGADTE-DSYTAM-PTFDTISVAVCVLT 275

  Fly   272 FFVLVFNFVLLETLGTSLTMDMFAWSNDEALWYMGIMMTTAAIVSLVTFVL----IEPMCKIIAE 332
            .|.|:|....|||:|:.....|:.|:|.:|:.|.||:.....:|.::.:.|    :........|
 Worm   276 QFTLMFIITNLETIGSLYAKMMWGWTNAQAVEYTGILQAVNGLVGVLVYALFAVKLGDYISQARE 340

  Fly   333 RYVLIWGGFSLMFLGRVLFV-----PWGPDPPKLAQPFNASWNLSESDPIFLGC-PTTQKWCGEL 391
            |...|:|    :.||.:..|     |||||.................|   ||| |....||
 Worm   341 RIFTIFG----LALGVLYHVVTYPYPWGPDLKYTTINVTIHGKNQTED---LGCNPAKYHWC--- 395

  Fly   392 PALTLTQFIIGFAFTSI-------GYPIGVTLIQTIFSKVLGPRPQGVWMGWMTGSGCLSRVLGP 449
               |.|:.:..:.:.|:       .:||....:.|:|||:||.|.||...|.|..:|..:|.:||
 Worm   396 ---TYTKDVNFWLYASMYGIVLAACFPIVNICMNTLFSKILGARRQGTMQGVMLMAGSFARTIGP 457

  Fly   450 VFVGSIYTRLG--TFWTFGVTSAMMLVSMFWL 479
            :.|..|:...|  ..|...:.: :.:.::||:
 Worm   458 LLVSWIFQEWGPEPIWIIEILT-LSITAIFWM 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cln7	NP_648107.3	MFS_MFSD8	37..487	CDD:340884	130/465 (28%)
mfsd-8.3	NP_001022903.1	MFS_MFSD8	48..495	CDD:340884	130/465 (28%)