Protein Alignment Cln7 and mfsd-8.2

DIOPT Version :10

• Sequence 1: NP_648107.3
• Gene: Cln7 / 38813
• FlyBaseID: FBgn0035767
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_505957.1
• Gene: mfsd-8.2 / 179602
• WormBaseID: WBGene00012280
• Length: 484
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 144/532 - (27%)
• Similarity: 245/532 - (46%)
• Gaps: 80/532 - (15%)

  Fly     8 SARFETKRLPE-DVDDGLETLEEYKQRWRSVRIIYFTMFLMALGFSIILTGIWPYLNKLDPDAGK 71
            ||.|:|..|.. .|......|:..|..|.|:.......:...|..|:..|.:||||.||||.|..
 Worm     4 SADFDTSSLKSYTVSTSRTNLDVRKSNWTSLWFANLIQYFCGLQMSLYFTSMWPYLLKLDPTAQL 68

  Fly    72 EFMGLIVAANPLGQMIFSPIFGWWGNKLGKIRLPLLLSLSLFTLASGIYSSLELRPDNVKYWMLS 136
            .|.|:|:|:..:||.:.|||||.|..|....::|:...|....:.:.:|..|......|::.||.
 Worm    69 PFFGIILASFSIGQAVGSPIFGTWTQKTESFKVPVATGLVFCCVGNILYGILPTIMWEVQWLMLV 133

  Fly   137 SRFLIGVSSANIALCRSYLSAATRISERTHAVAMVSLAQVLGFIIGPTLQAAVTPLGDQGHVWLW 201
            ||.|||..:.|::..|:|::|::.:.:|..||::.:.:||.|.:.||.||.|...:||  .|.::
 Worm   134 SRVLIGFGAGNLSALRAYVAASSTLEDRNTAVSLATGSQVTGMLTGPILQTAFAFIGD--GVRVF 196

  Fly   202 GKMHFNMYTASGW----INVLMSIGNFMMF---LPGVFEEHKIAAREVMVMQGGTSEKETWKGIK 259
            .....:.||:..:    :.::|::..|..|   ..||.:|                :||....|.
 Worm   197 NTFDLDAYTSPAFVLSIVLIIMAVMIFFYFSEDYAGVIDE----------------KKEDSDVII 245

  Fly   260 PSY--LSAWTLIVAFFVLVFNFVLLETLGTSLTMDMFAWSNDEALWYMGIMMTTAAIVSLVTFVL 322
            |.:  .:|...|..:||:....|.:|:|.:..|:.|:.|::.:|:.|.|.:.|.:..:|:..:::
 Worm   246 PPFDRRAAVVCIFLWFVIQTIAVNIESLCSVFTIAMYNWTSHQAIVYGGYIETASCALSVSQYLV 310

  Fly   323 IEPMCKI--IAERYVLIWGGFSLMF-LGRVLFVPWGPDPPKLAQPFNASWNLSESDPIFLGCPTT 384
            | .:.::  |.:|..:::|  .::| :..|:.:||...|..|.      :|.:.:|.   .|  |
 Worm   311 I-GLTRVGKIDKRIQILFG--CIVFCIYYVVLLPWPFYPESLL------YNPNVTDG---AC--T 361

  Fly   385 QKWCGELPALTLTQFII------GFAFTSIGYPIGVTLIQTIFSKVLGPRPQGVWMGWMTGSGCL 443
            .:||..:|.:....:|:      |.||..||..||     |:||:|||||.||...|.....|.:
 Worm   362 YEWCQYVPKIPFIAYILVYVLCFGIAFPYIGNSIG-----TLFSEVLGPRQQGTMQGVFAFFGSV 421

  Fly   444 SRVLGPVFVGSIYTRLGTFW------TFGVTSAMMLVSMFWLQCSNRLLIPPTFEKTTPVEL--- 499
            .|...|:.....:...|..|      ||.:..|:. ..:||.|             ..|:||
 Worm   422 GRCAAPLVTTFFFNSSGYTWVSVEMLTFLIIGALS-TCIFWKQ-------------MIPLELIQK 472

  Fly   500 -KELNKHNGSKL 510
             :.::.:|..|:
 Worm   473 KESISNNNNHKV 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cln7	NP_648107.3	MFS_MFSD8	37..487	CDD:340884	129/473 (27%)
mfsd-8.2	NP_505957.1	MFS_MFSD8	34..465	CDD:340884	129/481 (27%)