Protein Alignment Cln7 and C25E10.5

DIOPT Version :10

• Sequence 1: NP_648107.3
• Gene: Cln7 / 38813
• FlyBaseID: FBgn0035767
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_505338.1
• Gene: C25E10.5 / 179280
• WormBaseID: WBGene00016095
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 125/525 - (23%)
• Similarity: 236/525 - (44%)
• Gaps: 71/525 - (13%)

  Fly     5 RRVSARFETKRLPEDVDDGLETLEEYKQRWRSVRIIYFTMFLMALGFSIILTGIWPYLNKLDPDA 69
            ||.|.:.::..:|:..|         ...||.:.:......|.|:..|::..|.|||:.::|.||
 Worm    13 RRTSVKKDSLVVPDSED---------TTNWRLIIVAGIVSALNAVENSVLGIGEWPYMKEIDKDA 68

  Fly    70 GKEFMGLIVAANPLGQMIFSPIFGWWGNKLGKIRLPLLLSLSLFTLASGIYSSLELRPDNVKYWM 134
            ..:|.|:..:|:..|..:|:.:|..|..|...:::|||.|..:..:|..||.|:|..|.|.:|.:
 Worm    69 TAQFFGMATSASKCGHALFALVFSIWSYKTHSVKIPLLTSRLIAIVACVIYLSIEYVPVNKRYVL 133

  Fly   135 LSSRFLIGVSSANIALCRSYLSAATRISERTHAVAMVSLAQVLGFIIGPTLQAAVTPLGDQGHVW 199
            :|...|:|::::...:.|.|::..:...:|..|.|::.|:.::..::|||||...:.:...|:..
 Worm   134 MSVYILLGIANSATTVLRGYIAMCSSTQDRPRAFAVIGLSIIVSIVVGPTLQLIFSSIAYPGYEI 198

  Fly   200 LWGKMHFNMYTASGWINVLMS------IGNFMMFLPGVFEEHKIAAREVMVMQGGTSEKETWKGI 258
            :.| :.|::|:|..|.:.:::      ||.|:..:.....|.||.......|......|||...:
 Worm   199 MPG-IRFHIYSAPIWFSFILTILTAVFIGFFLQDVHRASTESKIEEESSRPMFSMEQLKETIATL 262

  Fly   259 KPSYLSAWTLI-VAFFVLV---FNFVLLETLGTSLTMDMFAWSNDEALWYMGIMMTTAAIVSLVT 319
            |.|.|. |:|| |..||.:   |:...::::.:.|.|..:.|:..|.:....::|....::|.|.
 Worm   263 KRSNLD-WSLIGVCLFVKIAATFSHATMQSIMSILFMVQYGWTGTETVRMGSMLMVCFGVLSCVV 326

  Fly   320 FVLIEPMCK---IIAERYVLIWGGFSLMFLGRVLFVPWGPDPPKLAQPFNASWNLSESDPIFL-- 379
             :|:...|:   |:.::.|.:   ...:..|.|..:.:         |:..|     |.|:.|
 Worm   327 -LLLYIFCRLGQILPQQKVFL---VCTIASGCVFLITY---------PYEFS-----SKPVVLYN 373

  Fly   380 -----GC-PTTQKWCGELPALTLTQF-IIGFAFTSIGYPIGVTLIQTIFSKVLGPRPQGVWMGWM 437
                 || |....||....|:....| |:....::...|:..|.:.|::|::||...|.|..|.|
 Worm   374 ETTHAGCNPVEYSWCETAVAVNPYFFMIVSIIVSAPSIPMMHTALDTVYSRILGNVDQSVAQGAM 438

  Fly   438 TGSGCLSRVLGPVFVGSIYTRLGT--FWTFGVTSAMMLVSMFWLQCSNRLLIPPTFEKTTPVELK 500
            |....:..::.|:|..:::|.||.  .|.. .:|....::..|.                 :.||
 Worm   439 TIVDDIVFMVTPIFTTTMFTLLGVGPLWLI-KSSVFFAIAAVWF-----------------LNLK 485

  Fly   501 ELNKH 505
            ::..|
 Worm   486 KITTH 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cln7	NP_648107.3	MFS_MFSD8	37..487	CDD:340884	115/473 (24%)
C25E10.5	NP_505338.1	MFS_MFSD8	36..487	CDD:340884	117/488 (24%)